产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
OPRK1多克隆抗体
目录 :
44-302G
规格 :
100微升
价格 :
美国450
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学
更多信息或购买 :
文章摘录数: 3
参考文献
Lorente J, Cuitavi J, Campos Jurado Y, Mont xf3 n Molina R, Gonz xe1 lez Romero J, Hip xf3 lito L. Kappa opioid receptor blockade in the nucleus accumbens shell prevents sex-dependent alcohol deprivation effect induced by inflammatory pain. Pain. 2022;163:e137-e147 pubmed 出版商
Hestehave S, Abelson K, Brønnum Pedersen T, Finn D, Andersson D, Munro G. The influence of rat strain on the development of neuropathic pain and comorbid anxio-depressive behaviour after nerve injury. Sci Rep. 2020;10:20981 pubmed 出版商
Zádor F, Lénárt N, Csibrány B, Sántha M, Molnár M, Tuka B, et al. Low dosage of rimonabant leads to anxiolytic-like behavior via inhibiting expression levels and G-protein activity of kappa opioid receptors in a cannabinoid receptor independent manner. Neuropharmacology. 2015;89:298-307 pubmed
产品信息
产品类型 :
抗体
产品名称 :
OPRK1多克隆抗体
目录# :
44-302G
规格 :
100微升
价格 :
美国450
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
小鼠, 大鼠
应用 :
Immunocytochemistry: 1:250, Immunofluorescence: 1:250, Western Blot: 1:1000
物种 :
小鼠, 大鼠
抗体亚型 :
IgG
储存 :
-20°C
描述 :
This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
免疫原 :
The antiserum was produced against a chemically synthesized peptide derived from the internal region of the mouse k-opioid receptor. The sequence is conserved in rat.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:250, Immunofluorescence: 1:250, Western Blot: 1:1000
别名 :
kappa opioid receptor; kappa-type opioid receptor; KOPR1; KOR; K-OR-1; KOR-1; MSL-1; Opiate receptor, kappa-1; opioid receptor kappa 1; opioid receptor, kappa 1; opioid receptor, kappa 2; OPRK; Oprk1; Oprk2; Ork1; R21; Ror-d
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国