磷酸化哺乳动物雷帕霉素靶蛋白(Ser2448)多克隆抗体

产品简要

公司名称 :

赛默飞世尔

其他品牌 :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

产品类型 :

抗体

产品名称 :

磷酸化哺乳动物雷帕霉素靶蛋白(Ser2448)多克隆抗体

44-1125G

规格 :

100微升

价格 :

美国500

克隆性 :

多克隆

宿主 :

domestic rabbit

共轭标签 :

未共轭

抗原修饰 :

磷酸化

反应物种 :

人类, 小鼠

应用 :

免疫印迹, 免疫细胞化学

更多信息或购买 :

赛默飞世尔产品网页

文章摘录数: 12

参考文献
Li H, Guan B, Liu S, Liu H, Song L, Zhang G, et al. PTPN14 promotes gastric cancer progression by PI3KA/AKT/mTOR pathway. Cell Death Dis. 2023;14:188 pubmed 出版商
Ibrahim W, Kamel A, Wahid A, Abdelkader N. Dapagliflozin as an autophagic enhancer via LKB1/AMPK/SIRT1 pathway in ovariectomized/D-galactose Alzheimer's rat model. Inflammopharmacology. 2022;30:2505-2520 pubmed 出版商
Lee S, Han J, Yang J, Jun H, Bang J, Shin H, et al. Role of mTORC1 activity during early retinal development and lamination in human-induced pluripotent stem cell-derived retinal organoids. Cell Death Discov. 2022;8:56 pubmed 出版商
Wilczek M, Armstrong F, Mayberry C, King B, Maginnis M. PI3K/AKT/mTOR Signaling Pathway Is Required for JCPyV Infection in Primary Astrocytes. Cells. 2021;10: pubmed 出版商
Cheng L, Zhu X, Liu Y, Zhu K, Lin K, Li F. ACSL4 contributes to sevoflurane-induced ferroptotic neuronal death in SH-SY5Y cells via the 5' AMP-activated protein kinase/mammalian target of rapamycin pathway. Ann Transl Med. 2021;9:1454 pubmed 出版商
Li S, Qin C, Chen Y, Wei D, Tan Z, Meng J. Implications of cell division cycle associated 4 on the Wilm's tumor cells viability via AKT/mTOR signaling pathway. Ren Fail. 2021;43:1470-1478 pubmed 出版商
Hermanowicz J, Pawlak K, Sieklucka B, Czarnomysy R, Kwiatkowska I, Kazberuk A, et al. MM-129 as a Novel Inhibitor Targeting PI3K/AKT/mTOR and PD-L1 in Colorectal Cancer. Cancers (Basel). 2021;13: pubmed 出版商
Ali R, Al Zahrani H, Barhoumi T, Alhallaj A, Mashhour A, Alshammari M, et al. Isolation and Establishment of a Highly Proliferative, Cancer Stem Cell-Like, and Naturally Immortalized Triple-Negative Breast Cancer Cell Line, KAIMRC2. Cells. 2021;10: pubmed 出版商
Ma Y, Jing J, Feng J, Yuan Y, Wen Q, Han X, et al. Ror2-mediated non-canonical Wnt signaling regulates Cdc42 and cell proliferation during tooth root development. Development. 2021;148: pubmed 出版商
An Y, Liu H, Zhou Z, Wang J, Jiang G, Li Z, et al. Sinoporphyrin sodium is a promising sensitizer for photodynamic and sonodynamic therapy in glioma. Oncol Rep. 2020;44:1596-1604 pubmed 出版商
Ye T, Wei L, Shi J, Jiang K, Xu H, Hu L, et al. Sirtuin1 activator SRT2183 suppresses glioma cell growth involving activation of endoplasmic reticulum stress pathway. BMC Cancer. 2019;19:706 pubmed 出版商
Zhao Z, Ma J, Mao Y, Dong L, Li S, Zhang Y. Silence of α1-Antitrypsin Inhibits Migration and Proliferation of Triple Negative Breast Cancer Cells. Med Sci Monit. 2018;24:6851-6860 pubmed 出版商

产品信息

产品类型 :

抗体

产品名称 :

磷酸化哺乳动物雷帕霉素靶蛋白(Ser2448)多克隆抗体

目录# :

44-1125G

规格 :

100微升

价格 :

美国500

克隆性 :

多克隆

纯度 :

抗原亲和色谱

宿主 :

兔

反应物种 :

人类, 小鼠

应用 :

Immunocytochemistry: 1:250, Immunofluorescence: 1:250, Western Blot: 1:1000

物种 :

人类, 小鼠

抗体亚型 :

IgG

储存 :

-20°C

描述 :

Mammalian target of rapamycin (mTOR) is a serine/threonine kinase that plays a key role in cell growth, cell proliferation, and protein synthesis. mTOR mediates phosphoinositide 3-kinase and Akt/PKB signaling, resulting in phosphorylation of 4EBP1, and initiation of mRNA translation. A second pathway involves regulation of ribosomal S6 kinase, which affects ribosome biogenesis and translation elongation. Mutations affecting the gene results in Smith-Kingsmore syndrome.

免疫原 :

The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human mTOR that contains serine 2448. The sequence is conserved in human, mouse and rat.

格式 :

液体

应用w/稀释 :

Immunocytochemistry: 1:250, Immunofluorescence: 1:250, Western Blot: 1:1000

别名 :

2610315D21Rik; AI327068; angiopoietin-like factor CDT6; FK506 binding protein 12-rapamycin associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; FKBP12-rapamycin complex-associated protein 1; FKBP-rapamycin associated protein; FKBP-rapamycin associated protein (FRAP); FKBP-rapamycin-associated protein FRAP; flat; FRAP; Frap1; FRAP2; Mammalian target of rapamycin; mechanistic target of rapamycin; mechanistic target of rapamycin (serine/threonine kinase); mechanistic target of rapamycin kinase; MTOR; m-TOR; mTORC1; RAFT1; Rapamycin and FKBP12 target 1; rapamycin and FKBP12 target-1 protein; rapamycin associated protein FRAP2; rapamycin target protein 1; RAPT1; serine/threonine-protein kinase mTOR; SKS

更多信息或购买 :

赛默飞世尔产品网页

公司信息

赛默飞世尔

上海浦东新金桥路27号7号楼

analyze.cn@thermofisher.com

http://www.thermo.com.cn

1084193588

公司总部: 美国