产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
水闸蛋白7单克隆抗体(5D10F3)
目录 :
37-4800
规格 :
100微克
价格 :
美国450.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
5D10F3
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 17
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类
Watari A, Hashegawa M, Yagi K, Kondoh M. Homoharringtonine increases intestinal epithelial permeability by modulating specific claudin isoforms in Caco-2 cell monolayers. Eur J Pharm Biopharm. 2015;89:232-8 pubmed 出版商
  • 免疫组化; 人类; 1:50; 图 1
Ma F, Ding X, Fan Y, Ying J, Zheng S, Lu N, et al. A CLDN1-negative phenotype predicts poor prognosis in triple-negative breast cancer. PLoS ONE. 2014;9:e112765 pubmed 出版商
  • 免疫印迹; 人类; 图 11
Kinoshita S, Kawasaki S, Kitazawa K, Shinomiya K. Establishment of a human conjunctival epithelial cell line lacking the functional TACSTD2 gene (an American Ophthalmological Society thesis). Trans Am Ophthalmol Soc. 2012;110:166-77 pubmed
  • 免疫组化-石蜡切片; 人类; 1:1000; 图 1
Victoria H, Henrik E, Lennart B, Lennart F. Claudin 1 and Claudin 7 Gene Polymorphisms and Protein Derangement are Unrelated to the Growth Pattern and Tumor Volume of Colon Carcinoma. Int J Biomed Sci. 2010;6:96-102 pubmed
  • 免疫印迹; 人类; 1:500; 图 S4
Krishnan M, Lapierre L, Knowles B, Goldenring J. Rab25 regulates integrin expression in polarized colonic epithelial cells. Mol Biol Cell. 2013;24:818-31 pubmed 出版商
  • 免疫组化; 人类; 图 4
Ohe C, Kuroda N, Takasu K, Senzaki H, Shikata N, Yamaguchi T, et al. Utility of immunohistochemical analysis of KAI1, epithelial-specific antigen, and epithelial-related antigen for distinction of chromophobe renal cell carcinoma, an eosinophilic variant from renal oncocytoma. Med Mol Morphol. 2012;45:98-104 pubmed 出版商
  • 免疫组化; 人类; 图 3
Lisch W, Bron A, Munier F, Schorderet D, Tiab L, Lange C, et al. Franceschetti hereditary recurrent corneal erosion. Am J Ophthalmol. 2012;153:1073-81.e4 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5
Comamala M, Pinard M, Theriault C, Matte I, Albert A, Boivin M, et al. Downregulation of cell surface CA125/MUC16 induces epithelial-to-mesenchymal transition and restores EGFR signalling in NIH:OVCAR3 ovarian carcinoma cells. Br J Cancer. 2011;104:989-99 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:400; 图 3
Carvalho J, Wasco M, Kunju L, Thomas D, Shah R. Cluster analysis of immunohistochemical profiles delineates CK7, vimentin, S100A1 and C-kit (CD117) as an optimal panel in the differential diagnosis of renal oncocytoma from its mimics. Histopathology. 2011;58:169-79 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5
  • 免疫组化; 人类; 图 2
  • 免疫印迹; 人类; 图 2
Nakatsukasa M, Kawasaki S, Yamasaki K, Fukuoka H, Matsuda A, Tsujikawa M, et al. Tumor-associated calcium signal transducer 2 is required for the proper subcellular localization of claudin 1 and 7: implications in the pathogenesis of gelatinous drop-like corneal dystrophy. Am J Pathol. 2010;177:1344-55 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50; 图 4a
  • 免疫细胞化学; 人类; 图 4h
Tassi R, Bignotti E, Falchetti M, Ravanini M, Calza S, Ravaggi A, et al. Claudin-7 expression in human epithelial ovarian cancer. Int J Gynecol Cancer. 2008;18:1262-71 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 1
Sauer T, Pedersen M, Ebeltoft K, Naess O. Reduced expression of Claudin-7 in fine needle aspirates from breast carcinomas correlate with grading and metastatic disease. Cytopathology. 2005;16:193-8 pubmed
Hollis P, Mobley R, Bhuju J, Abell A, Sutter C, Sutter T. CYP1B1 Augments the Mesenchymal, Claudin-Low, and Chemoresistant Phenotypes of Triple-Negative Breast Cancer Cells. Int J Mol Sci. 2022;23: pubmed 出版商
Ozawa M, Hiver S, Yamamoto T, Shibata T, Upadhyayula S, Mimori Kiyosue Y, et al. Adherens junction regulates cryptic lamellipodia formation for epithelial cell migration. J Cell Biol. 2020;219: pubmed 出版商
Ahmad R, Rah B, Bastola D, Dhawan P, Singh A. Obesity-induces Organ and Tissue Specific Tight Junction Restructuring and Barrier Deregulation by Claudin Switching. Sci Rep. 2017;7:5125 pubmed 出版商
Wu C, Feng X, Lu M, Morimura S, Udey M. Matriptase-mediated cleavage of EpCAM destabilizes claudins and dysregulates intestinal epithelial homeostasis. J Clin Invest. 2017;127:623-634 pubmed 出版商
Kirk A, Campbell S, Bass P, Mason J, Collins J. Differential expression of claudin tight junction proteins in the human cortical nephron. Nephrol Dial Transplant. 2010;25:2107-19 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
水闸蛋白7单克隆抗体(5D10F3)
目录# :
37-4800
规格 :
100微克
价格 :
美国450.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类, 小鼠
应用 :
ELISA: Assay-dependent, Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Paraffin): 1:50-1:500, Immunoprecipitation: Assay-dependent, Western Blot: 2 µg/mL
物种 :
人类, 小鼠
克隆 :
5D10F3
抗体亚型 :
IgG2a, kappa
储存 :
-20°C
描述 :
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.
免疫原 :
Synthetic peptide derived from the C-terminal region of the human claudin-7 protein.
格式 :
液体
应用w/稀释 :
ELISA: Assay-dependent, Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Paraffin): 1:50-1:500, Immunoprecipitation: Assay-dependent, Western Blot: 2 µg/mL
别名 :
CEPTRL2; claudin 7; claudin-1; Claudin-7; Cldn7; CLDN-7; clostridium perfringens enterotoxin receptor-like 2; CPETRL2; Hs.84359
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国