产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
水闸蛋白7多克隆抗体
目录 :
34-9100
规格 :
100微克
价格 :
美国482
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠,
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 38
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 1:250; 图 4d
  • 免疫印迹; 小鼠; 1:20,000; 图 4a
Marincola Smith P, Choksi Y, Markham N, Hanna D, Zi J, Weaver C, et al. Colon epithelial cell TGFβ signaling modulates the expression of tight junction proteins and barrier function in mice. Am J Physiol Gastrointest Liver Physiol. 2021;320:G936-G957 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 s7c
Wijshake T, Zou Z, Chen B, Zhong L, Xiao G, Xie Y, et al. Tumor-suppressor function of Beclin 1 in breast cancer cells requires E-cadherin. Proc Natl Acad Sci U S A. 2021;118: pubmed 出版商
  • 免疫细胞化学; 犬; 图 2
  • 免疫印迹; 犬; 图 2
Tokuda S, Hirai T, Furuse M. Claudin-4 knockout by TALEN-mediated gene targeting in MDCK cells: Claudin-4 is dispensable for the permeability properties of tight junctions in wild-type MDCK cells. PLoS ONE. 2017;12:e0182521 pubmed 出版商
  • 免疫印迹; 犬; 1:250; 图 2d
Raya Sandino A, Castillo Kauil A, Domínguez Calderón A, Alarcón L, Flores Benitez D, Cuellar Perez F, et al. Zonula occludens-2 regulates Rho proteins activity and the development of epithelial cytoarchitecture and barrier function. Biochim Biophys Acta Mol Cell Res. 2017;1864:1714-1733 pubmed 出版商
  • 免疫印迹; 人类; 图 6c
Wu C, Feng X, Lu M, Morimura S, Udey M. Matriptase-mediated cleavage of EpCAM destabilizes claudins and dysregulates intestinal epithelial homeostasis. J Clin Invest. 2017;127:623-634 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 1e
  • 免疫细胞化学; 人类; 1:200; 图 2h
  • 免疫印迹; 人类; 1:1000; 图 s2a
Salomon J, Gaston C, Magescas J, Duvauchelle B, Canioni D, Sengmanivong L, et al. Contractile forces at tricellular contacts modulate epithelial organization and monolayer integrity. Nat Commun. 2017;8:13998 pubmed 出版商
  • 流式细胞仪; 人类; 1:100; 图 3a
Torres Martínez A, Gallardo Vera J, Lara Holguin A, Montano L, Rendón Huerta E. Claudin-6 enhances cell invasiveness through claudin-1 in AGS human adenocarcinoma gastric cancer cells. Exp Cell Res. 2017;350:226-235 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2a
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 6e
  • 免疫印迹; 小鼠; 1:1000; 图 6a
Lin Z, Zhang Y, Xia Y, Xu X, Jiao X, Sun J. Salmonella enteritidis Effector AvrA Stabilizes Intestinal Tight Junctions via the JNK Pathway. J Biol Chem. 2016;291:26837-26849 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 3
Virág J, Haberler C, Baksa G, Piurko V, Hegedûs Z, Reiniger L, et al. Region Specific Differences of Claudin-5 Expression in Pediatric Intracranial Ependymomas: Potential Prognostic Role in Supratentorial Cases. Pathol Oncol Res. 2017;23:245-252 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5
Dianati E, Poiraud J, Weber Ouellette A, Plante I. Connexins, E-cadherin, Claudin-7 and ?-catenin transiently form junctional nexuses during the post-natal mammary gland development. Dev Biol. 2016;416:52-68 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Teo W, Merino V, Cho S, Korangath P, Liang X, Wu R, et al. HOXA5 determines cell fate transition and impedes tumor initiation and progression in breast cancer through regulation of E-cadherin and CD24. Oncogene. 2016;35:5539-5551 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 1
Gu L, Cong J, Zhang J, Tian Y, Zhai X. A microwave antigen retrieval method using two heating steps for enhanced immunostaining on aldehyde-fixed paraffin-embedded tissue sections. Histochem Cell Biol. 2016;145:675-80 pubmed 出版商
  • 免疫组化; 人类; 图 4
  • 免疫印迹; 人类; 图 1c
Barbáchano A, Fernández Barral A, Pereira F, Segura M, Ordóñez Morán P, Carrillo de Santa Pau E, et al. SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150. Oncogene. 2016;35:2991-3003 pubmed 出版商
Wei xdf F, Czichos C, Knobe L, Voges L, Bojarski C, Michel G, et al. MarvelD3 Is Upregulated in Ulcerative Colitis and Has Attenuating Effects during Colitis Indirectly Stabilizing the Intestinal Barrier. Cells. 2022;11: pubmed 出版商
Droessler L, Cornelius V, Markov A, Amasheh S. Tumor Necrosis Factor Alpha Effects on the Porcine Intestinal Epithelial Barrier Include Enhanced Expression of TNF Receptor 1. Int J Mol Sci. 2021;22: pubmed 出版商
Nelson J, McDonough A, Xiang Z, Ralph D, Robertson J, Giani J, et al. Local and downstream actions of proximal tubule angiotensin II signaling on Na+ transporters in the mouse nephron. Am J Physiol Renal Physiol. 2021;321:F69-F81 pubmed 出版商
Tinh N, Sitolo G, Yamamoto Y, Suzuki T. Citrus limon Peel Powder Reduces Intestinal Barrier Defects and Inflammation in a Colitic Murine Experimental Model. Foods. 2021;10: pubmed 出版商
Faux M, King L, Kane S, Love C, Sieber O, Burgess A. APC regulation of ESRP1 and p120-catenin isoforms in colorectal cancer cells. Mol Biol Cell. 2021;32:120-130 pubmed 出版商
El Chami C, Foster A, Johnson C, Clausen R, Cornwell P, Haslam I, et al. Organic osmolytes increase expression of specific tight junction proteins in skin and alter barrier function in keratinocytes. Br J Dermatol. 2021;184:482-494 pubmed 出版商
Borisova M, Achasova K, Morozova K, Andreyeva E, Litvinova E, Ogienko A, et al. Mucin-2 knockout is a model of intercellular junction defects, mitochondrial damage and ATP depletion in the intestinal epithelium. Sci Rep. 2020;10:21135 pubmed 出版商
Wu C, Lu M, Feng X, Nakato G, Udey M. Matriptase Cleaves EpCAM and TROP2 in Keratinocytes, Destabilizing Both Proteins and Associated Claudins. Cells. 2020;9: pubmed 出版商
Kumai A, Tsugami Y, Wakasa H, Suzuki N, Suzuki T, Nishimura T, et al. Adverse Effects of Coumestrol and Genistein on Mammary Morphogenesis and Future Milk Production Ability of Mammary Epithelial Cells. Adv Biosyst. 2020;4:e1900187 pubmed 出版商
Dahiya N. Amyloid precursor-like protein 2 interacts with claudin-7 and affects ovarian cancer cell survival. Future Sci OA. 2020;6:FSO457 pubmed 出版商
Ley D, Desseyn J, Gouyer V, Plet S, Tims S, Renes I, et al. Early life nutrition influences susceptibility to chronic inflammatory colitis in later life. Sci Rep. 2019;9:18111 pubmed 出版商
Tulyeu J, Kumagai H, Jimbo E, Watanabe S, Yokoyama K, Cui L, et al. Probiotics Prevents Sensitization to Oral Antigen and Subsequent Increases in Intestinal Tight Junction Permeability in Juvenile-Young Adult Rats. Microorganisms. 2019;7: pubmed 出版商
Miranda J, Martín Tapia D, Valdespino Vazquez Y, Alarcón L, Espejel Nuñez A, Guzmán Huerta M, et al. Syncytiotrophoblast of Placentae from Women with Zika Virus Infection Has Altered Tight Junction Protein Expression and Increased Paracellular Permeability. Cells. 2019;8: pubmed 出版商
Otani T, Nguyen T, Tokuda S, Sugihara K, Sugawara T, Furuse K, et al. Claudins and JAM-A coordinately regulate tight junction formation and epithelial polarity. J Cell Biol. 2019;218:3372-3396 pubmed 出版商
Luo S, Terciolo C, Bracarense A, Payros D, Pinton P, Oswald I. In vitro and in vivo effects of a mycotoxin, deoxynivalenol, and a trace metal, cadmium, alone or in a mixture on the intestinal barrier. Environ Int. 2019;132:105082 pubmed 出版商
Yoon N, Dadson K, Dang T, Chu T, Noskovičová N, Hinz B, et al. Tracking adiponectin biodistribution via fluorescence molecular tomography indicates increased vascular permeability after streptozotocin-induced diabetes. Am J Physiol Endocrinol Metab. 2019;317:E760-E772 pubmed 出版商
Danzinger S, Tan Y, Rudas M, Kastner M, Weingartshofer S, Muhr D, et al. Association of Cytokeratin 5 and Claudin 3 expression with BRCA1 and BRCA2 germline mutations in women with early breast cancer. BMC Cancer. 2019;19:695 pubmed 出版商
Suzuki K, Sentani K, Tanaka H, Yano T, Suzuki K, Oshima M, et al. Deficiency of Stomach-Type Claudin-18 in Mice Induces Gastric Tumor Formation Independent of H pylori Infection. Cell Mol Gastroenterol Hepatol. 2019;8:119-142 pubmed 出版商
Chen H, Lu R, Zhang Y, Sun J. Vitamin D Receptor Deletion Leads to the Destruction of Tight and Adherens Junctions in Lungs. Tissue Barriers. 2018;6:1-13 pubmed 出版商
Barth A, Kim H, Riedel Kruse I. Regulation of epithelial migration by epithelial cell adhesion molecule requires its Claudin-7 interaction domain. PLoS ONE. 2018;13:e0204957 pubmed 出版商
Shimada H, Satohisa S, Kohno T, Konno T, Takano K, Takahashi S, et al. Downregulation of lipolysis-stimulated lipoprotein receptor promotes cell invasion via claudin-1-mediated matrix metalloproteinases in human endometrial cancer. Oncol Lett. 2017;14:6776-6782 pubmed 出版商
Nguyen N, Fernando S, Biette K, Hammer J, Capocelli K, Kitzenberg D, et al. TGF-β1 alters esophageal epithelial barrier function by attenuation of claudin-7 in eosinophilic esophagitis. Mucosal Immunol. 2018;11:415-426 pubmed 出版商
Kern M, Günzel D, Aschenbach J, Tedin K, Bondzio A, Lodemann U. Altered Cytokine Expression and Barrier Properties after In Vitro Infection of Porcine Epithelial Cells with Enterotoxigenic Escherichia coli and Probiotic Enterococcus faecium. Mediators Inflamm. 2017;2017:2748192 pubmed 出版商
Tokuda S, Furuse M. Claudin-2 knockout by TALEN-mediated gene targeting in MDCK cells: claudin-2 independently determines the leaky property of tight junctions in MDCK cells. PLoS ONE. 2015;10:e0119869 pubmed 出版商
Patsialou A, Wang Y, Pignatelli J, Chen X, Entenberg D, Oktay M, et al. Autocrine CSF1R signaling mediates switching between invasion and proliferation downstream of TGF? in claudin-low breast tumor cells. Oncogene. 2015;34:2721-31 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
水闸蛋白7多克隆抗体
目录# :
34-9100
规格 :
100微克
价格 :
美国482
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
狗, 人类, 小鼠
应用 :
ELISA: Assay-dependent, Immunocytochemistry: 2-3 µg/mL, Immunohistochemistry: Assay-dependent, Western Blot: 1.5 - 3 µg/mL
物种 :
狗, 人类, 小鼠
抗体亚型 :
IgG
储存 :
-20°C
描述 :
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.
免疫原 :
Synthetic peptide derived from the C-terminal region of the human claudin-7 protein.
格式 :
液体
应用w/稀释 :
ELISA: Assay-dependent, Immunocytochemistry: 2-3 µg/mL, Immunohistochemistry: Assay-dependent, Western Blot: 1.5 - 3 µg/mL
别名 :
CEPTRL2; claudin 7; claudin-1; Claudin-7; Cldn7; CLDN-7; clostridium perfringens enterotoxin receptor-like 2; CPETRL2; Hs.84359
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国