产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD336 (NKp44) Monoclonal Antibody (44.189), APC, eBioscience™
目录 :
17-3369-42
规格 :
100试验
价格 :
美国349
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
APC
克隆名称 :
44.189
反应物种 :
人类
应用 :
流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 6
参考文献
Hudspeth K, Silva Santos B, Mavilio D. Natural cytotoxicity receptors: broader expression patterns and functions in innate and adaptive immune cells. Front Immunol. 2013;4:69 pubmed 出版商
Rosental B, Brusilovsky M, Hadad U, Oz D, Appel M, Afergan F, et al. Proliferating cell nuclear antigen is a novel inhibitory ligand for the natural cytotoxicity receptor NKp44. J Immunol. 2011;187:5693-702 pubmed 出版商
Poggi A, Massaro A, Negrini S, Contini P, Zocchi M. Tumor-induced apoptosis of human IL-2-activated NK cells: role of natural cytotoxicity receptors. J Immunol. 2005;174:2653-60 pubmed
Campbell K, Yusa S, Kikuchi Maki A, Catina T. NKp44 triggers NK cell activation through DAP12 association that is not influenced by a putative cytoplasmic inhibitory sequence. J Immunol. 2004;172:899-906 pubmed
Cantoni C, Bottino C, Vitale M, Pessino A, Augugliaro R, Malaspina A, et al. NKp44, a triggering receptor involved in tumor cell lysis by activated human natural killer cells, is a novel member of the immunoglobulin superfamily. J Exp Med. 1999;189:787-96 pubmed
Vitale M, Bottino C, Sivori S, Sanseverino L, Castriconi R, Marcenaro E, et al. NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells, is involved in non-major histocompatibility complex-restricted tumor cell lysis. J Exp Med. 1998;187:2065-72 pubmed
产品信息
产品类型 :
抗体
产品名称 :
CD336 (NKp44) Monoclonal Antibody (44.189), APC, eBioscience™
目录# :
17-3369-42
规格 :
100试验
价格 :
美国349
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 5 µL (0.25 µg)/test
物种 :
人类
克隆 :
44.189
抗体亚型 :
IgG2b, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
CD336 is also known as NKp44 or NCR2. CD336 is a 44-kDa transmembrane glycoprotein belonging to the natural cytotoxicity receptor (NCR) family and contains an ITIM domain located in the cytoplasmic tail. Expression of CD336 and NK cell activation by the receptor requires association with DAP12, an ITAM-containing transmembrane accessory protein. Once thought to be expressed exclusively on IL-2-activated NK cells and a subset of gamma delta T lymphocytes, studies have shown expression of CD336 on IL-3-stimulated plasmacytoid dendritic cells, alpha beta T cells in the small intestinal epithelium, and T cells in cord blood. CD336 has been shown to be involved in the innate response of activated NK cells against viral infection and tumor cell proliferation.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 5 µL (0.25 µg)/test
别名 :
CD336; CD336 antigen; dJ149M18.1; LY95; lymphocyte antigen 95 (activating NK-receptor; NK-p44); Lymphocyte antigen 95 homolog; lymphocyte antigen 95 homolog (activating NK-receptor; NK-p44); natural cytotoxicity triggering receptor 2; Natural killer cell p44-related protein; natural killer cell receptor; NCR2; NK cell activating receptor (NKp44); NK cell-activating receptor; NKP44; NK-p44; NK-p44dJ149M18.1
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国