产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD366 (TIM3) Monoclonal Antibody (F38-2E2), APC, eBioscience™
目录 :
17-3109-41
规格 :
25试验
价格 :
美国156
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
APC
克隆名称 :
F38-2E2
反应物种 :
人类
应用 :
流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 17
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 1:100
Deng M, Gui X, Kim J, Xie L, Chen W, Li Z, et al. LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration. Nature. 2018;562:605-609 pubmed 出版商
  • 流式细胞仪; 人类; 图 6
Pachnio A, Ciáurriz M, Begum J, Lal N, Zuo J, Beggs A, et al. Cytomegalovirus Infection Leads to Development of High Frequencies of Cytotoxic Virus-Specific CD4+ T Cells Targeted to Vascular Endothelium. PLoS Pathog. 2016;12:e1005832 pubmed 出版商
  • 流式细胞仪; 人类
Weist B, Wehler P, El Ahmad L, Schmueck Henneresse M, Millward J, Nienen M, et al. A revised strategy for monitoring BKV-specific cellular immunity in kidney transplant patients. Kidney Int. 2015;88:1293-1303 pubmed 出版商
Cascone T, Leung C, Weissferdt A, Pataer A, Carter B, Godoy M, et al. Neoadjuvant chemotherapy plus nivolumab with or without ipilimumab in operable non-small cell lung cancer: the phase 2 platform NEOSTAR trial. Nat Med. 2023;29:593-604 pubmed 出版商
Wang X, Yu X, Li W, Neeli P, Liu M, Li L, et al. Expanding anti-CD38 immunotherapy for lymphoid malignancies. J Exp Clin Cancer Res. 2022;41:210 pubmed 出版商
Xiong J, Wang N, Zhong H, Cui B, Cheng S, Sun R, et al. SLC1A1 mediated glutamine addiction and contributed to natural killer T-cell lymphoma progression with immunotherapeutic potential. EBioMedicine. 2021;72:103614 pubmed 出版商
Yu L, Liu X, Wang X, Yan F, Wang P, Jiang Y, et al. TIGIT+ TIM-3+ NK cells are correlated with NK cell exhaustion and disease progression in patients with hepatitis B virus‑related hepatocellular carcinoma. Oncoimmunology. 2021;10:1942673 pubmed 出版商
YEKU O, Rao T, Laster I, Kononenko A, Purdon T, Wang P, et al. Bispecific T-Cell Engaging Antibodies Against MUC16 Demonstrate Efficacy Against Ovarian Cancer in Monotherapy and in Combination With PD-1 and VEGF Inhibition. Front Immunol. 2021;12:663379 pubmed 出版商
Wang D, Prager B, Gimple R, Aguilar B, Alizadeh D, Tang H, et al. CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies. Cancer Discov. 2021;11:1192-1211 pubmed 出版商
Mitchell K, Diao L, Karpinets T, Negrao M, Tran H, Parra E, et al. Neutrophil expansion defines an immunoinhibitory peripheral and intratumoral inflammatory milieu in resected non-small cell lung cancer: a descriptive analysis of a prospectively immunoprofiled cohort. J Immunother Cancer. 2020;8: pubmed 出版商
Rovituso D, Scheffler L, Wunsch M, Kleinschnitz C, Dörck S, Ulzheimer J, et al. CEACAM1 mediates B cell aggregation in central nervous system autoimmunity. Sci Rep. 2016;6:29847 pubmed 出版商
Forget M, Malu S, Liu H, Toth C, Maiti S, Kale C, et al. Activation and propagation of tumor-infiltrating lymphocytes on clinical-grade designer artificial antigen-presenting cells for adoptive immunotherapy of melanoma. J Immunother. 2014;37:448-60 pubmed 出版商
Ma C, Li G, Cheng Y, Wang J, Ying R, Shi L, et al. Cis association of galectin-9 with Tim-3 differentially regulates IL-12/IL-23 expressions in monocytes via TLR signaling. PLoS ONE. 2013;8:e72488 pubmed 出版商
Gooden M, Wiersma V, Samplonius D, Gerssen J, van Ginkel R, Nijman H, et al. Galectin-9 activates and expands human T-helper 1 cells. PLoS ONE. 2013;8:e65616 pubmed 出版商
Hastings W, Anderson D, Kassam N, Koguchi K, Greenfield E, Kent S, et al. TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines. Eur J Immunol. 2009;39:2492-501 pubmed 出版商
Su E, Lin J, Kane L. TIM-1 and TIM-3 proteins in immune regulation. Cytokine. 2008;44:9-13 pubmed 出版商
Koguchi K, Anderson D, Yang L, O Connor K, Kuchroo V, Hafler D. Dysregulated T cell expression of TIM3 in multiple sclerosis. J Exp Med. 2006;203:1413-8 pubmed
产品信息
产品类型 :
抗体
产品名称 :
CD366 (TIM3) Monoclonal Antibody (F38-2E2), APC, eBioscience™
目录# :
17-3109-41
规格 :
25试验
价格 :
美国156
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 5 µL (0.06 µg)/test
物种 :
人类
克隆 :
F38-2E2
抗体亚型 :
IgG1, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
TIM3 (Hepatitis A virus cellular receptor 2, HAVCR2, T-cell immunoglobulin, mucin-dmain containing-3) is a 281 amino acid long, Type-1 Th1- specific cell surface glycoprotein expressed on terminally differentiated CD4+Th1 and CD8+Tc1 cells. TIM3 consists of an IgV-like domain, a mucin-like domain in the extracellular region, and a conserved Tyrosine phosphorylation motif in the cytoplasmic region. TIM3 is involved in macrophage activation and induction of autoimmune diseases. Further, TIM3 down-regulates aggressive Th1-mediated immune responses and facilitates in the development of immune tolerance. Pathological significance of TIM3 has been attributed to Experimental autoimmune encephalomyelitis (EAE), a Th-1 dependent autoimmune disease, and also enhances the severity of experimental autoimmune encephalomyelitis in mice.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 5 µL (0.06 µg)/test
别名 :
CD366; FLJ14428; Havcr2; HAVcr-2; Hepatitis A virus cellular receptor 2; hepatitis A virus cellular receptor 2 homolog; kidney injury molecule-3; KIM-3; sCD366; soluble CD366; soluble TIM 3; T cell immunoglobulin mucin 3; T cell immunoglobulin mucin-3; T-cell immunoglobulin and mucin domain containing 3; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin family member 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; TIM3; TIM-3; TIMD3; TIMD-3
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国