产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
c-Met Monoclonal Antibody (eBioclone 7), eBioscience™
目录 :
14-8854-80
规格 :
25微克
价格 :
美国116
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
eBioclone 7
反应物种 :
小鼠
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 7
参考文献 |
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产品信息
产品类型 :
抗体
产品名称 :
c-Met Monoclonal Antibody (eBioclone 7), eBioscience™
目录# :
14-8854-80
规格 :
25微克
价格 :
美国116
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 1 µg/test
物种 :
小鼠
克隆 :
eBioclone 7
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
MET is a tyrosine kinase receptor for the hepatocyte growth factor. It is linked to functions such as cell proliferation, scattering, morphogenesis, and survival. Ligand binding at the cell surface induces autophosphorylation of MET that provides docking sites for downstream signaling molecules. After activation of the ligand, MET interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, and STAT3. There interactions lead to the activation of signaling cascades including RAS-ERK, PI3, kinase-AKT, and PLCgamma-PKC. MET plays a role in embryonic development including gastrulation, development of muscles and neurons, angiogenesis, and kidney formation. It also plays a role in adults including wound healing, organ regeneration, and tissue remodeling. MET has been linked to cancers including gastric, renal, and breast; therefore, making it a target for cancer therapeutics and diagnostic testing.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1 µg/test
别名 :
AI838057; AUTS9; bHLHe59; CG1705; CG1705 gene product from transcript CG1705-RB; CG1705-PA; CG1705-PB; cMet; c-met; DFNB97; Dmel CG1705; Dmel_CG1705; DmMet; EC 2.7.10.1; Hepatocyte growth factor receptor; HGF; HGF receptor; HGF receptor c-Met; HGF/SF receptor; Hgfr; HGF-SF receptor; juvenile hormone resistance; Met; met proto-oncogene; met proto-oncogene (hepatocyte growth factor receptor); met proto-oncogene tyrosine kinase; MET proto-oncogene, receptor tyrosine kinase; Met/Met1; methoprene tolerant; Methoprene-tolerant; Methoprene-tolerant protein; Met-PA; Met-PB; Mett; oncogene MET; Par4; proto-oncogene c-Met; RCCP2; resistance (1) juvenile H; resistance to juvenile hormone; Rst(1)JH; sc MET; Scatter factor receptor; SF receptor; soluble c met; Tyrosine-protein kinase Met
更多信息或购买 :
公司信息
赛默飞世尔
产品浏览
- c-Met Monoclonal Antibody (eBioclone 7), eBioscience™ | 14-8854-82
- c-Met Monoclonal Antibody (eBioclone 97), eBioscience™ | 14-8858-82
- TRA-1-60 (Podocalyxin) Monoclonal Antibody (TRA-1-60), eBioscience™ | 14-8863-82
- TRA-1-81 (Podocalyxin) Monoclonal Antibody (TRA-1-81), eBioscience™ | 14-8883-82
- Cytokeratin Pan Type II Monoclonal Antibody (AE3), eBioscience™ | 14-9000-82
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