产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD103 (Integrin alpha E) Monoclonal Antibody (2E7), Biotin, eBioscience™
目录 :
13-1031-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
仓鼠
共轭标签 :
生物素
克隆名称 :
2E7
反应物种 :
小鼠
应用 :
免疫组化, 流式细胞仪, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 19
参考文献
Tong D, Zhang L, Ning F, Xu Y, Hu X, Shi Y. Contact-dependent delivery of IL-2 by dendritic cells to CD4 T cells in the contraction phase promotes their long-term survival. Protein Cell. 2020;11:108-123 pubmed 出版商
Rosato P, Wijeyesinghe S, Stolley J, Nelson C, Davis R, Manlove L, et al. Virus-specific memory T cells populate tumors and can be repurposed for tumor immunotherapy. Nat Commun. 2019;10:567 pubmed 出版商
Funk K, Klein R. CSF1R antagonism limits local restimulation of antiviral CD8+ T cells during viral encephalitis. J Neuroinflammation. 2019;16:22 pubmed 出版商
Kawasaki T, Ito K, Miyata H, Akira S, Kawai T. Deletion of PIKfyve alters alveolar macrophage populations and exacerbates allergic inflammation in mice. EMBO J. 2017;36:1707-1718 pubmed 出版商
Lyons Cohen M, Thomas S, Cook D, Nakano H. Precision-cut Mouse Lung Slices to Visualize Live Pulmonary Dendritic Cells. J Vis Exp. 2017;: pubmed 出版商
Chudnovskiy A, Mortha A, Kana V, Kennard A, Ramírez J, Rahman A, et al. Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome. Cell. 2016;167:444-456.e14 pubmed 出版商
Menendez C, Jinkins J, Carr D. Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency. J Immunol. 2016;197:1262-75 pubmed 出版商
Ochi T, Feng Y, Kitamoto S, Nagao Kitamoto H, Kuffa P, Atarashi K, et al. Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine. Sci Rep. 2016;6:27634 pubmed 出版商
Clatworthy M, Aronin C, Mathews R, Morgan N, Smith K, Germain R. Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes. Nat Med. 2014;20:1458-63 pubmed 出版商
Qin Q, Wang Z, Pan P, Cao Z, Xia Q, Tan H, et al. Lung dendritic cells undergo maturation and polarization towards a T helper type 2-stimulating phenotype in a mouse model of asthma: Role of nerve growth factor. Exp Ther Med. 2014;8:1402-1408 pubmed
Nagaoka M, Hatta Y, Kawaoka Y, Malherbe L. Antigen signal strength during priming determines effector CD4 T cell function and antigen sensitivity during influenza virus challenge. J Immunol. 2014;193:2812-20 pubmed 出版商
Zhou Q, Ho A, Schlitzer A, Tang Y, Wong K, Wong F, et al. GM-CSF-licensed CD11b+ lung dendritic cells orchestrate Th2 immunity to Blomia tropicalis. J Immunol. 2014;193:496-509 pubmed 出版商
Oderup C, Lajevic M, Butcher E. Canonical and noncanonical Wnt proteins program dendritic cell responses for tolerance. J Immunol. 2013;190:6126-34 pubmed 出版商
Munoz Fontela C, Pazos M, Delgado I, Murk W, Mungamuri S, Lee S, et al. p53 serves as a host antiviral factor that enhances innate and adaptive immune responses to influenza A virus. J Immunol. 2011;187:6428-36 pubmed 出版商
Edelson B, Bradstreet T, Kc W, Hildner K, Herzog J, Sim J, et al. Batf3-dependent CD11b(low/-) peripheral dendritic cells are GM-CSF-independent and are not required for Th cell priming after subcutaneous immunization. PLoS ONE. 2011;6:e25660 pubmed 出版商
Smith K, Hochweller K, Hämmerling G, Boon L, MacDonald A, Maizels R. Chronic helminth infection promotes immune regulation in vivo through dominance of CD11cloCD103- dendritic cells. J Immunol. 2011;186:7098-109 pubmed 出版商
Edelson B, Kc W, Juang R, Kohyama M, Benoit L, Klekotka P, et al. Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8alpha+ conventional dendritic cells. J Exp Med. 2010;207:823-36 pubmed 出版商
Gupta S, Janani R, Bin Q, Luciw P, Greer C, Perri S, et al. Characterization of human immunodeficiency virus Gag-specific gamma interferon-expressing cells following protective mucosal immunization with alphavirus replicon particles. J Virol. 2005;79:7135-45 pubmed
Suzuki R, Nakao A, Kanamaru Y, Okumura K, Ogawa H, Ra C. Localization of intestinal intraepithelial T lymphocytes involves regulation of alphaEbeta7 expression by transforming growth factor-beta. Int Immunol. 2002;14:339-45 pubmed
产品信息
产品类型 :
抗体
产品名称 :
CD103 (Integrin alpha E) Monoclonal Antibody (2E7), Biotin, eBioscience™
目录# :
13-1031-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
亚美尼亚仓鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.25 µg/test, Immunohistochemistry (Frozen): Assay-Dependent
物种 :
小鼠
克隆 :
2E7
抗体亚型 :
IgG
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
CD103 (ITGAE, Integrin alpha E) is molecule that is expressed on mucosa-associated T lymphocytes and activated cells and on subet of TGF beta -1 cells. In particular, CD103 includes a 150kDa alpha chain and a 120kDa beta chain. CD103 is expressed by 0.5 to 2% of resting lymphocytes in peripheral blood and lymphoid organs. CD103 antibody stains a few bone marrow cells and, rarely, peripheral blood lymphocytes. CD103 is part of the integrin family which are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. ITGAE encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, CD103 protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. CD103 is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. Diseases associated with CD103 dysfunction include hairy cell leukemia and splenic marginal zone lymphoma.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.25 µg/test, Immunohistochemistry (Frozen): Assay-Dependent
别名 :
A530055J10; alpha-E1; alpha-M290; aM290; antigen CD103; antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide; CD103; DC; DCs; HML-1 antigen; human mucosal lymphocyte antigen 1, alpha polypeptide; HUMINAE; integrin alpha E; integrin alpha E, epithelial-associated; integrin alpha E1, epithelial-associated; integrin alpha M290; Integrin alpha-E; Integrin alpha-E heavy chain; Integrin alpha-E light chain; Integrin alpha-IEL; integrin subunit alpha E; integrin, alpha E; integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide); integrin, alpha E, epithelial-associated; Intregrin alpha E2; Itgae; MGC141996; Mucosal lymphocyte 1 antigen
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国