Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

蛋白

ERp72(人类),(重组)(多聚组氨酸标签)

ADI-SPP-721-050

50微克

ADI-SPP-721-050

ERp72(人类),(重组)(多聚组氨酸标签)

蛋白

50微克

Endoplasmic reticulum protein (ERp) 72 is a member of the protein disulfide isomerase (PDI) family that is localized to the endoplasmic reticulum. It contains three repeats of the thioredoxin-like regions that is postulated to represent three independently acting catalytic domains (CGHC) of PDI activity. ERp72 contains the sequence at its carboxyl terminus which serves as its ER retention signal. Together with other ER resident proteins such as BiP, GRP94, and PDI, they serve as the molecular chaperones for proper folding of newly translocated and glycolsylated proteins such as thyroglobulin (Tg) and human chorionic gonadotropin (hCG)-b. ERp72 expression is regulated by the level of misfolding proteins in the ER, as the amount of ERp72 increased in response to epithelial ischemia, a condition that perturbs the maturation of secretory proteins.

PDIA4, 蛋白质二硫键异构酶 A4

≥85%(十二烷基磺酸钠-PAGE;免疫印迹)

液体。 在50mM TRIS, pH值7.5, 含150mM氯化钠和1mM乙二胺四乙酸

Western blot control.

WB, Activity assay

-80°C