产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
整合素甲2(CD49b)
目录 :
P1H6
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
P1H6
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪
更多信息或购买 :
Developmental Studies Hybridoma Bank 产品网页
文章摘录数: 8
参考文献
Carragher N, Levkau B, Ross R, Raines E. Degraded collagen fragments promote rapid disassembly of smooth muscle focal adhesions that correlates with cleavage of pp125(FAK), paxillin, and talin. J Cell Biol. 1999;147:619-30 pubmed
Koyama H, Raines E, Bornfeldt K, Roberts J, Ross R. Fibrillar collagen inhibits arterial smooth muscle proliferation through regulation of Cdk2 inhibitors. Cell. 1996;87:1069-78 pubmed
Skubitz A, Bast R, Wayner E, Letourneau P, Wilke M. Expression of alpha 6 and beta 4 integrins in serous ovarian carcinoma correlates with expression of the basement membrane protein laminin. Am J Pathol. 1996;148:1445-61 pubmed
Symington B, Takada Y, Carter W. Interaction of integrins alpha 3 beta 1 and alpha 2 beta 1: potential role in keratinocyte intercellular adhesion. J Cell Biol. 1993;120:523-35 pubmed
Flickinger K, Judware R, Lechner R, Carter W, Culp L. Integrin expression in human neuroblastoma cells with or without N-myc amplification and in ectopic/orthotopic nude mouse tumors. Exp Cell Res. 1994;213:156-63 pubmed
Skinner M, Raines E, Ross R. Dynamic expression of alpha 1 beta 1 and alpha 2 beta 1 integrin receptors by human vascular smooth muscle cells. Alpha 2 beta 1 integrin is required for chemotaxis across type I collagen-coated membranes. Am J Pathol. 1994;145:1070-81 pubmed
Wayner E, Carter W. Identification of multiple cell adhesion receptors for collagen and fibronectin in human fibrosarcoma cells possessing unique alpha and common beta subunits. J Cell Biol. 1987;105:1873-84 pubmed
Carter W, Wayner E, Bouchard T, Kaur P. The role of integrins alpha 2 beta 1 and alpha 3 beta 1 in cell-cell and cell-substrate adhesion of human epidermal cells. J Cell Biol. 1990;110:1387-404 pubmed
产品信息
内部号码 :
7742
名称 :
P1H6
Depositor Name :
Wayner, E.A. / Carter, W.G.
Depositor Institution :
Fred Hutchison Cancer Research Center
Date Deposited :
10/11/11
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
整合素甲2(CD49b)
抗原物种 :
人类
宿主物种 :
小鼠
抗体亚型 :
MIgG3
Isotype for catalog (legacy) :
IgG3
Positive Tested Species Reactivity :
人类
Species Tested (legacy) :
人类
Initial Publication Pubmed ID :
2822727
Depositor Notes (Special Instructions) :
Immunostaining with frozen or acetone fixation. Doesn't work for FFPE. No function inhibition.
Collections :
CD抗原, 细胞粘附, 人类
搜索关键词 :
Wayner, E.A. / Carter, W.G., integrin alpha 2 (CD49b), Human, MIgG3, Human, ITGA2, BR, GPIa, CD49B, HPA-5, VLA-2, VLAA2, AB_2619599, monoclonal, Cell adhesion/Cluster Determinant antigens/Human, Immunohistochemistry/Immunofluorescence/Western Blot/Immunoprecipitation/FACS
抗原分子量 :
Predicted: 129 kDa; Apparent: 150 kDa
基因 :
ITGA2
Alternate Gene Name(s) :
BR, 血小板表面胶原蛋白受体, CD49B, HPA-5, VLA-2, VLAA2
UniProt数据库编号 :
P17301
抗体登记处号码 :
AB_2619599
Synonyms (Alternate Clone Names) :
CD49b
免疫原 :
人类HT-1080纤维肉瘤细胞
免疫原序列 :
全长蛋白
克隆性 :
单克隆
Myeloma Strain :
NS-1/狐狸-NY
表位定位 :
No
Recommended Applications :
流式细胞仪, 免疫荧光, 免疫组化, 免疫沉淀, 免疫印迹
Immunoblotting (legacy) :
yes
免疫组化PubMed IDs :
1691191 8623916
免疫荧光PubMed IDs :
1691191 8421064
免疫印迹PubMed IDs :
8421064
免疫沉淀PubMed IDs :
2822727 8421064 8020586
流式细胞仪PubMed IDs :
7977639 8020586
PubMed IDs :
8978611 10545505
其他信息 :
P1H6 recognizes an epitope that requires activation of the alpha2/beta1 complex.
DSHB增长培养基 :
RPMI
References (legacy) :
J. Cell. Biol. 105, 1873-1884.; J. Cell Biol. 109(1), 397-407.; J Cell Biol 110, 1387-1404.; Cell 87, 1069-1078.; J. Cell Biol. 147, 619-629.; Methods in Enzymology 42, 117-153.
更多信息或购买 :
Developmental Studies Hybridoma Bank 产品网页
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构，为生命科学研究领域及诊断领域，提供高质量的抗体等产品。