产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
CD63(人类)LAMP-3
目录 :
H5C6
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
H5C6
反应物种 :
人类, 小鼠, 大鼠, 狗, 猪
应用 :
酶联免疫吸附测定, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 流式细胞仪, 其他
更多信息或购买 :
Developmental Studies Hybridoma Bank 产品网页
文章摘录数: 30
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 7b
Son K, Mukherjee M, McIntyre B, Eguez J, Radford K, LaVigne N, et al. Improved recovery of functionally active eosinophils and neutrophils using novel immunomagnetic technology. J Immunol Methods. 2017;449:44-55 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 ev2a
Wilhelm L, Wendling C, Vedie B, Kobayashi T, Chenard M, Tomasetto C, et al. STARD3 mediates endoplasmic reticulum-to-endosome cholesterol transport at membrane contact sites. EMBO J. 2017;36:1412-1433 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3a
Stephen J, Yokoyama T, Tolman N, O Brien K, Nicoli E, Brooks B, et al. Cellular and molecular defects in a patient with Hermansky-Pudlak syndrome type 5. PLoS ONE. 2017;12:e0173682 pubmed 出版商
  • 其他; 人类; 图 3
Su W, Kowalczyk A. The VE-cadherin cytoplasmic domain undergoes proteolytic processing during endocytosis. Mol Biol Cell. 2017;28:76-84 pubmed 出版商
  • 免疫细胞化学; 大鼠; 图 1c
López Montero N, Ramos Marquès E, Risco C, Garcia del Portillo F. Intracellular Salmonella induces aggrephagy of host endomembranes in persistent infections. Autophagy. 2016;12:1886-1901 pubmed
  • 流式细胞仪; 人类; 图 1
Ventress J, Partridge L, Read R, Cozens D, MacNeil S, Monk P. Peptides from Tetraspanin CD9 Are Potent Inhibitors of Staphylococcus Aureus Adherence to Keratinocytes. PLoS ONE. 2016;11:e0160387 pubmed 出版商
  • 免疫细胞化学; 猪; 1:25; 图 4a
Hernaez B, Guerra M, Salas M, Andres G. African Swine Fever Virus Undergoes Outer Envelope Disruption, Capsid Disassembly and Inner Envelope Fusion before Core Release from Multivesicular Endosomes. PLoS Pathog. 2016;12:e1005595 pubmed 出版商
  • 免疫细胞化学; 狗; 1:100; 图 3
Carrasco Ramírez P, Greening D, Andrés G, Gopal S, Martín Villar E, Renart J, et al. Podoplanin is a component of extracellular vesicles that reprograms cell-derived exosomal proteins and modulates lymphatic vessel formation. Oncotarget. 2016;7:16070-89 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s4
Rebsamen M, Pochini L, Stasyk T, de Araújo M, Galluccio M, Kandasamy R, et al. SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1. Nature. 2015;519:477-81 pubmed 出版商
Sadovska L, Zandberga E, Sagini K, JÄ“kabsons K, Riekstiņa U, Kalniņa Z, et al. A novel 3D heterotypic spheroid model for studying extracellular vesicle-mediated tumour and immune cell communication. Biochem Biophys Res Commun. 2018;495:1930-1935 pubmed 出版商
Royo F, Zuñiga García P, Torrano V, Loizaga A, Sánchez Mosquera P, Ugalde Olano A, et al. Transcriptomic profiling of urine extracellular vesicles reveals alterations of CDH3 in prostate cancer. Oncotarget. 2016;7:6835-46 pubmed 出版商
Shtanko O, Nikitina R, Altuntas C, Chepurnov A, Davey R. Crimean-Congo hemorrhagic fever virus entry into host cells occurs through the multivesicular body and requires ESCRT regulators. PLoS Pathog. 2014;10:e1004390 pubmed 出版商
Hessvik N, Phuyal S, Brech A, Sandvig K, Llorente A. Profiling of microRNAs in exosomes released from PC-3 prostate cancer cells. Biochim Biophys Acta. 2012;1819:1154-63 pubmed 出版商
Bastos Amador P, Royo F, Gonzalez E, Conde Vancells J, Palomo Diez L, Borras F, et al. Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability. J Proteomics. 2012;75:3574-84 pubmed 出版商
Lässer C, O Neil S, Ekerljung L, Ekström K, Sjöstrand M, Lotvall J. RNA-containing exosomes in human nasal secretions. Am J Rhinol Allergy. 2011;25:89-93 pubmed 出版商
Flannery A, Czibener C, Andrews N. Palmitoylation-dependent association with CD63 targets the Ca2+ sensor synaptotagmin VII to lysosomes. J Cell Biol. 2010;191:599-613 pubmed 出版商
Krementsov D, Weng J, Lambelé M, Roy N, Thali M. Tetraspanins regulate cell-to-cell transmission of HIV-1. Retrovirology. 2009;6:64 pubmed 出版商
Parthasarathy V, Martin F, Higginbottom A, Murray H, Moseley G, Read R, et al. Distinct roles for tetraspanins CD9, CD63 and CD81 in the formation of multinucleated giant cells. Immunology. 2009;127:237-48 pubmed 出版商
Logozzi M, De Milito A, Lugini L, Borghi M, Calabro L, Spada M, et al. High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients. PLoS ONE. 2009;4:e5219 pubmed 出版商
Bampton E, Goemans C, Niranjan D, Mizushima N, Tolkovsky A. The dynamics of autophagy visualized in live cells: from autophagosome formation to fusion with endo/lysosomes. Autophagy. 2005;1:23-36 pubmed
Nydegger S, Khurana S, Krementsov D, Foti M, Thali M. Mapping of tetraspanin-enriched microdomains that can function as gateways for HIV-1. J Cell Biol. 2006;173:795-807 pubmed
Huber V, Fais S, Iero M, Lugini L, Canese P, Squarcina P, et al. Human colorectal cancer cells induce T-cell death through release of proapoptotic microvesicles: role in immune escape. Gastroenterology. 2005;128:1796-804 pubmed
Duffield A, Kamsteeg E, Brown A, Pagel P, Caplan M. The tetraspanin CD63 enhances the internalization of the H,K-ATPase beta-subunit. Proc Natl Acad Sci U S A. 2003;100:15560-5 pubmed
Ackerman A, Kyritsis C, Tampe R, Cresswell P. Early phagosomes in dendritic cells form a cellular compartment sufficient for cross presentation of exogenous antigens. Proc Natl Acad Sci U S A. 2003;100:12889-94 pubmed
Arunachalam B, Phan U, Geuze H, Cresswell P. Enzymatic reduction of disulfide bonds in lysosomes: characterization of a gamma-interferon-inducible lysosomal thiol reductase (GILT). Proc Natl Acad Sci U S A. 2000;97:745-50 pubmed
Serru V, Le Naour F, Billard M, Azorsa D, Lanza F, Boucheix C, et al. Selective tetraspan-integrin complexes (CD81/alpha4beta1, CD151/alpha3beta1, CD151/alpha6beta1) under conditions disrupting tetraspan interactions. Biochem J. 1999;340 ( Pt 1):103-11 pubmed
Scherberich A, Moog S, Haan Archipoff G, Azorsa D, Lanza F, Beretz A. Tetraspanin CD9 is associated with very late-acting integrins in human vascular smooth muscle cells and modulates collagen matrix reorganization. Arterioscler Thromb Vasc Biol. 1998;18:1691-7 pubmed
Hammond C, Denzin L, Pan M, Griffith J, Geuze H, Cresswell P. The tetraspan protein CD82 is a resident of MHC class II compartments where it associates with HLA-DR, -DM, and -DO molecules. J Immunol. 1998;161:3282-91 pubmed
Azorsa D, Hyman J, Hildreth J. CD63/Pltgp40: a platelet activation antigen identical to the stage-specific, melanoma-associated antigen ME491. Blood. 1991;78:280-4 pubmed
Hildreth J, Derr D, Azorsa D. Characterization of a novel self-associating Mr 40,000 platelet glycoprotein. Blood. 1991;77:121-32 pubmed
产品信息
内部号码 :
537
名称 :
H5C6
Depositor Name :
August, J.T. / Hildreth, J.E.K.
Depositor Institution :
The Johns Hopkins University School of Medicine
Date Deposited :
4/12/93
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
CD63(人类)LAMP-3
抗原物种 :
人类
宿主物种 :
小鼠
抗体亚型 :
MIgG1, kappa light chain
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
人类, 猪
Species Tested (legacy) :
人类
Initial Publication Pubmed ID :
1984792
Collections :
CD antigens,Cell signaling,Human,Neurodevelopment
搜索关键词 :
August, J.T. / Hildreth, J.E.K., CD63 (human) LAMP, Human, MIgG1, kappa light chain, Human/Porcine, CD63, MLA1, TSPAN30, ME491, LAMP-3, OMA81H, AB_528158, monoclonal, Cluster Determinant antigens/Human/Cell signaling, Immunofluorescence/Immunoprecipitation/ELISA/Function Blocking/FACS
抗原分子量 :
Predicted: 26 kDa; Apparent: heterodisperse glycoprotein of usually 40 to 55 kDa
基因 :
CD63
Alternate Gene Name(s) :
MLA1, TSPAN30, ME491, LAMP-3, OMA81H
UniProt数据库编号 :
P08962
抗体登记处号码 :
AB_528158
Synonyms (Alternate Clone Names) :
抗Pltg~4
免疫原 :
Human adherent spleen cells
免疫原序列 :
全长蛋白
克隆性 :
单克隆
Myeloma Strain :
P3X653-Ag8
表位定位 :
Yes
Epitope Location or Sequence :
Recognizes an extracellular epitope: extracellular domain 1 or 2, corresponding to aa 33-51 and 103-203, respectively.
Recommended Applications :
ELISA,FACS,Function Blocking,Immunofluorescence,Immunoprecipitation
Immunoblotting (legacy) :
yes
免疫荧光PubMed IDs :
16874023 25233119 14561893 10639150 9759843 31314175
免疫印迹PubMed IDs :
10229664 19381331 14660791 29248729 15940614 22516433 22982408 21041449 9759843
免疫沉淀PubMed IDs :
1984792 2070066 10229664 9759843
酶联免疫吸附测定PubMed IDs :
19381331
Function Blocking Pubmed IDs :
19489128
流式细胞仪PubMed IDs :
1984792 10229664 19381331 15940614 9812906 22516433 21172122
PubMed IDs :
25233119
其他信息 :
RRID:AB_528158
DSHB增长培养基 :
Iscove's
References (legacy) :
Anat. Rec. Part A 276A, 75-102.; Autophagy, 1(1), 23-36.; PLoS Pathog. 10(9): e1004390. doi:10.1371/journal.ppat.1004390.
更多信息或购买 :
Developmental Studies Hybridoma Bank 产品网页
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构，为生命科学研究领域及诊断领域，提供高质量的抗体等产品。