产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
troponin T (cardiac/slow)
目录 :
CT3
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
CT3
反应物种 :
人类, 小鼠, brown rat, bantam, 牛
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
文章摘录数: 21
出版应用/物种/样本/稀释 | 参考文献 |
---|---|
| |
| |
| |
| |
| |
| |
Mukherjee A, Wilson E, Rotwein P. Insulin-like growth factor (IGF) binding protein-5 blocks skeletal muscle differentiation by inhibiting IGF actions. Mol Endocrinol. 2008;22:206-15 pubmed
| |
Dagle J, Sabel J, Littig J, Sutherland L, Kolker S, Weeks D. Pitx2c attenuation results in cardiac defects and abnormalities of intestinal orientation in developing Xenopus laevis. Dev Biol. 2003;262:268-81 pubmed
| |
Jin J, Brotto M, Hossain M, Huang Q, Brotto L, Nosek T, et al. Truncation by Glu180 nonsense mutation results in complete loss of slow skeletal muscle troponin T in a lethal nemaline myopathy. J Biol Chem. 2003;278:26159-65 pubmed
| |
Dube M, Huot M, Khandjian E. Muscle specific fragile X related protein 1 isoforms are sequestered in the nucleus of undifferentiated myoblast. BMC Genet. 2000;1:4 pubmed
| |
Jin J, Chen A, Ogut O, Huang Q. Conformational modulation of slow skeletal muscle troponin T by an NH(2)-terminal metal-binding extension. Am J Physiol Cell Physiol. 2000;279:C1067-77 pubmed
| |
Kolker S, Tajchman U, Weeks D. Confocal imaging of early heart development in Xenopus laevis. Dev Biol. 2000;218:64-73 pubmed
| |
Wang D, Reiter R, Lin J, Wang Q, Williams H, Krob S, et al. Requirement of a novel gene, Xin, in cardiac morphogenesis. Development. 1999;126:1281-94 pubmed
| |
Jin J. Alternative RNA splicing-generated cardiac troponin T isoform switching: a non-heart-restricted genetic programming synchronized in developing cardiac and skeletal muscles. Biochem Biophys Res Commun. 1996;225:883-9 pubmed
| |
Warren K, Lin J. Forced expression and assembly of rat cardiac troponin T isoforms in cultured muscle and nonmuscle cells. J Muscle Res Cell Motil. 1993;14:619-32 pubmed
| |
Swiderski R, Solursh M. Precocious appearance of cardiac troponin T pre-mRNAs during early avian embryonic skeletal muscle development in ovo. Dev Biol. 1990;140:73-82 pubmed
|
产品信息
内部号码 :
2993
名称 :
CT3
Depositor Name :
Lin, J.J.-C.
Depositor Institution :
University of Iowa
Date Deposited :
1/2/96
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
troponin T (cardiac/slow)
抗原物种 :
牛
宿主物种 :
小鼠
抗体亚型 :
MIgG2a
Isotype for catalog (legacy) :
IgG2a
Positive Tested Species Reactivity :
Broad species,Chicken,Fish,Human,Mouse,Rabbit,Rat,Xenopus
Species Tested (legacy) :
broad-species specificity, Xenopus, rat, mouse, human
Initial Publication Pubmed ID :
2358124
Depositor Notes (Special Instructions) :
CT3 was initially published in: Jin, J., Lin, J.-C., and Lin, J.J.-C. (1990). Troponin T isoform switching during heart development. Ann. NY Acad. Sci. 588, 393-396.
Collections :
Cardiac development,Cell markers,Cytoskeleton,Human,Muscular dystrophy,Skeletal muscle,Xenopus
搜索关键词 :
Lin J.J.-C., troponin T (cardiac/slow), Bovine, MIgG2a, broad species/Xenopus/rat/mouse/human/chicken/rabbit/fish, TNNT2, , AB_528495, monoclonal, Cardiac development/Cytoskeletal elements/Muscular dystrophy/Xenopus/Cell markers/Skeletal muscle/Human, Immunohistochemistry/Immunofluorescence/Western Blot/FFPE
抗原分子量 :
Predicted (cTnT): 34 kDa; Apparent (cTnT): 43kDa
基因 :
TNNT2
UniProt数据库编号 :
P13789
抗体登记处号码 :
AB_528495
免疫原 :
Purified cardiac troponin T
免疫原序列 :
全长蛋白
克隆性 :
单克隆
Myeloma Strain :
NS1
表位定位 :
Yes
Epitope Location or Sequence :
氨基酸94-178
表位定位Pubmed登录号 :
20529660
Recommended Applications :
FFPE, 免疫荧光, 免疫组化, 免疫印迹
Immunoblotting (legacy) :
Single band from cardiac muscle
免疫组化PubMed IDs :
20549732 12732643 27144987 27144987
免疫荧光PubMed IDs :
2358124 8126222 10644411 14550790 18854137 10021346 17885206 29255592
免疫印迹PubMed IDs :
8126222 11178106 8780706 12732643 11003587 17885206 20529660
流式细胞仪PubMed IDs :
27131741
其他信息 :
CT3 recognizes the embryonic and adult cardiac isforms [PMID: 2358124]. CT3 cross-react with slow skeletal muscle TnT but doesn't recognize fast skeletal muscle TnT [PMID: 12732643].
DSHB增长培养基 :
RPMI
公司信息
Developmental Studies Hybridoma Bank
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构,为生命科学研究领域及诊断领域,提供高质量的抗体等产品。