产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
troponin T (cardiac/slow)
目录 :
CT3
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
CT3
反应物种 :
人类, 小鼠, brown rat, bantam, 牛
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
Developmental Studies Hybridoma Bank 产品网页
文章摘录数: 21
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 1:10; 图 3b
  • 免疫组化-冰冻切片; bantam; 1:10; 图 1h
Tang W, Martik M, Li Y, Bronner M. Cardiac neural crest contributes to cardiomyocytes in amniotes and heart regeneration in zebrafish. elife. 2019;8: pubmed 出版商
  • 免疫组化; brown rat; 图 7c
  • 免疫细胞化学; 小鼠; 图 5b
Maltabe V, Barka E, Kontonika M, Florou D, Kouvara Pritsouli M, Roumpi M, et al. Isolation of an ES-Derived Cardiovascular Multipotent Cell Population Based on VE-Cadherin Promoter Activity. Stem Cells Int. 2016;2016:8305624 pubmed 出版商
  • 免疫印迹; bantam; 1:100; 图 2d
Blech Hermoni Y, Sullivan C, Jenkins M, Wessely O, Ladd A. CUG-BP, Elav-like family member 1 (CELF1) is required for normal myofibrillogenesis, morphogenesis, and contractile function in the embryonic heart. Dev Dyn. 2016;245:854-73 pubmed 出版商
  • 免疫细胞化学; 人类; 4 ug/ml; 图 1
Eng G, Lee B, Protas L, Gagliardi M, Brown K, Kass R, et al. Autonomous beating rate adaptation in human stem cell-derived cardiomyocytes. Nat Commun. 2016;7:10312 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
Geula S, Moshitch Moshkovitz S, Dominissini D, Mansour A, Kol N, Salmon Divon M, et al. Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation. Science. 2015;347:1002-6 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500
Yuan B, Wan P, Chu D, Nie J, Cao Y, Luo W, et al. A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice. Am J Pathol. 2014;184:1967-80 pubmed 出版商
Liao S, Dong W, Lv L, Guo H, Yang J, Zhao H, et al. Heart regeneration in adult Xenopus tropicalis after apical resection. Cell Biosci. 2017;7:70 pubmed 出版商
Chan S, Chan H, Kyba M. Heterogeneity of Mesp1+ mesoderm revealed by single-cell RNA-seq. Biochem Biophys Res Commun. 2016;474:469-475 pubmed 出版商
Haremaki T, Sridharan J, Dvora S, Weinstein D. Regulation of vertebrate embryogenesis by the exon junction complex core component Eif4a3. Dev Dyn. 2010;239:1977-87 pubmed 出版商
Jin J, Chong S. Localization of the two tropomyosin-binding sites of troponin T. Arch Biochem Biophys. 2010;500:144-50 pubmed 出版商
Drenckhahn J, Schwarz Q, Gray S, Laskowski A, Kiriazis H, Ming Z, et al. Compensatory growth of healthy cardiac cells in the presence of diseased cells restores tissue homeostasis during heart development. Dev Cell. 2008;15:521-33 pubmed 出版商
Mukherjee A, Wilson E, Rotwein P. Insulin-like growth factor (IGF) binding protein-5 blocks skeletal muscle differentiation by inhibiting IGF actions. Mol Endocrinol. 2008;22:206-15 pubmed
Dagle J, Sabel J, Littig J, Sutherland L, Kolker S, Weeks D. Pitx2c attenuation results in cardiac defects and abnormalities of intestinal orientation in developing Xenopus laevis. Dev Biol. 2003;262:268-81 pubmed
Jin J, Brotto M, Hossain M, Huang Q, Brotto L, Nosek T, et al. Truncation by Glu180 nonsense mutation results in complete loss of slow skeletal muscle troponin T in a lethal nemaline myopathy. J Biol Chem. 2003;278:26159-65 pubmed
Dube M, Huot M, Khandjian E. Muscle specific fragile X related protein 1 isoforms are sequestered in the nucleus of undifferentiated myoblast. BMC Genet. 2000;1:4 pubmed
Jin J, Chen A, Ogut O, Huang Q. Conformational modulation of slow skeletal muscle troponin T by an NH(2)-terminal metal-binding extension. Am J Physiol Cell Physiol. 2000;279:C1067-77 pubmed
Kolker S, Tajchman U, Weeks D. Confocal imaging of early heart development in Xenopus laevis. Dev Biol. 2000;218:64-73 pubmed
Wang D, Reiter R, Lin J, Wang Q, Williams H, Krob S, et al. Requirement of a novel gene, Xin, in cardiac morphogenesis. Development. 1999;126:1281-94 pubmed
Jin J. Alternative RNA splicing-generated cardiac troponin T isoform switching: a non-heart-restricted genetic programming synchronized in developing cardiac and skeletal muscles. Biochem Biophys Res Commun. 1996;225:883-9 pubmed
Warren K, Lin J. Forced expression and assembly of rat cardiac troponin T isoforms in cultured muscle and nonmuscle cells. J Muscle Res Cell Motil. 1993;14:619-32 pubmed
Swiderski R, Solursh M. Precocious appearance of cardiac troponin T pre-mRNAs during early avian embryonic skeletal muscle development in ovo. Dev Biol. 1990;140:73-82 pubmed
产品信息
内部号码 :
2993
名称 :
CT3
Depositor Name :
Lin, J.J.-C.
Depositor Institution :
University of Iowa
Date Deposited :
1/2/96
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
troponin T (cardiac/slow)
抗原物种 :
牛
宿主物种 :
小鼠
抗体亚型 :
MIgG2a
Isotype for catalog (legacy) :
IgG2a
Positive Tested Species Reactivity :
Broad species,Chicken,Fish,Human,Mouse,Rabbit,Rat,Xenopus
Species Tested (legacy) :
broad-species specificity, Xenopus, rat, mouse, human
Initial Publication Pubmed ID :
2358124
Depositor Notes (Special Instructions) :
CT3 was initially published in: Jin, J., Lin, J.-C., and Lin, J.J.-C. (1990). Troponin T isoform switching during heart development. Ann. NY Acad. Sci. 588, 393-396.
Collections :
Cardiac development,Cell markers,Cytoskeleton,Human,Muscular dystrophy,Skeletal muscle,Xenopus
搜索关键词 :
Lin J.J.-C., troponin T (cardiac/slow), Bovine, MIgG2a, broad species/Xenopus/rat/mouse/human/chicken/rabbit/fish, TNNT2, , AB_528495, monoclonal, Cardiac development/Cytoskeletal elements/Muscular dystrophy/Xenopus/Cell markers/Skeletal muscle/Human, Immunohistochemistry/Immunofluorescence/Western Blot/FFPE
抗原分子量 :
Predicted (cTnT): 34 kDa; Apparent (cTnT): 43kDa
基因 :
TNNT2
UniProt数据库编号 :
P13789
抗体登记处号码 :
AB_528495
免疫原 :
Purified cardiac troponin T
免疫原序列 :
全长蛋白
克隆性 :
单克隆
Myeloma Strain :
NS1
表位定位 :
Yes
Epitope Location or Sequence :
氨基酸94-178
表位定位Pubmed登录号 :
20529660
Recommended Applications :
FFPE, 免疫荧光, 免疫组化, 免疫印迹
Immunoblotting (legacy) :
Single band from cardiac muscle
免疫组化PubMed IDs :
20549732 12732643 27144987 27144987
免疫荧光PubMed IDs :
2358124 8126222 10644411 14550790 18854137 10021346 17885206 29255592
免疫印迹PubMed IDs :
8126222 11178106 8780706 12732643 11003587 17885206 20529660
流式细胞仪PubMed IDs :
27131741
其他信息 :
CT3 recognizes the embryonic and adult cardiac isforms [PMID: 2358124]. CT3 cross-react with slow skeletal muscle TnT but doesn't recognize fast skeletal muscle TnT [PMID: 12732643].
DSHB增长培养基 :
RPMI
更多信息或购买 :
Developmental Studies Hybridoma Bank 产品网页
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构，为生命科学研究领域及诊断领域，提供高质量的抗体等产品。