产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
原肌球蛋白, TPM1
目录 :
CGbeta6
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
CGbeta6
反应物种 :
人类, 鸡
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
Developmental Studies Hybridoma Bank 产品网页
文章摘录数: 19
参考文献
Glass J, Phillips P, Gunning P, Stehn J. Hypoxia alters the recruitment of tropomyosins into the actin stress fibres of neuroblastoma cells. BMC Cancer. 2015;15:712 pubmed 出版商
Prunotto M, Bruschi M, Gunning P, Gabbiani G, Weibel F, Ghiggeri G, et al. Stable incorporation of α-smooth muscle actin into stress fibers is dependent on specific tropomyosin isoforms. Cytoskeleton (Hoboken). 2015;72:257-67 pubmed 出版商
Liu R, Feng H, Jin J. Physiological contractility of cardiomyocytes in the wall of mouse and rat azygos vein. Am J Physiol Cell Physiol. 2014;306:C697-704 pubmed 出版商
Schevzov G, Whittaker S, Fath T, Lin J, Gunning P. Tropomyosin isoforms and reagents. Bioarchitecture. 2011;1:135-164 pubmed
Gallant C, Appel S, Graceffa P, Leavis P, Lin J, Gunning P, et al. Tropomyosin variants describe distinct functional subcellular domains in differentiated vascular smooth muscle cells. Am J Physiol Cell Physiol. 2011;300:C1356-65 pubmed 出版商
Lin J, Eppinga R, Warren K, McCrae K. Human tropomyosin isoforms in the regulation of cytoskeleton functions. Adv Exp Med Biol. 2008;644:201-22 pubmed
Das K, Bajpai M. Tropomyosins in human diseases: ulcerative colitis. Adv Exp Med Biol. 2008;644:158-67 pubmed
Mirza Z, Sastri B, Lin J, Amenta P, Das K. Autoimmunity against human tropomyosin isoforms in ulcerative colitis: localization of specific human tropomyosin isoforms in the intestine and extraintestinal organs. Inflamm Bowel Dis. 2006;12:1036-43 pubmed
Eppinga R, Li Y, Lin J, Lin J. Tropomyosin and caldesmon regulate cytokinesis speed and membrane stability during cell division. Arch Biochem Biophys. 2006;456:161-74 pubmed
O Hara S, Lin J. Accumulation of tropomyosin isoform 5 at the infection sites of host cells during Cryptosporidium invasion. Parasitol Res. 2006;99:45-54 pubmed
DesMarais V, Ichetovkin I, Condeelis J, Hitchcock Degregori S. Spatial regulation of actin dynamics: a tropomyosin-free, actin-rich compartment at the leading edge. J Cell Sci. 2002;115:4649-60 pubmed
Geng X, Biancone L, Dai H, Lin J, Yoshizaki N, Dasgupta A, et al. Tropomyosin isoforms in intestinal mucosa: production of autoantibodies to tropomyosin isoforms in ulcerative colitis. Gastroenterology. 1998;114:912-22 pubmed
Pelham R, Lin J, Wang Y. A high molecular mass non-muscle tropomyosin isoform stimulates retrograde organelle transport. J Cell Sci. 1996;109 ( Pt 5):981-9 pubmed
Novy R, Liu L, Lin C, Helfman D, Lin J. Expression of smooth muscle and nonmuscle tropomyosins in Escherichia coli and characterization of bacterially produced tropomyosins. Biochim Biophys Acta. 1993;1162:255-65 pubmed
Warren K, Lin J, McDermott J, Lin J. Forced expression of chimeric human fibroblast tropomyosin mutants affects cytokinesis. J Cell Biol. 1995;129:697-708 pubmed
Lin J, Chou C, Lin J. Monoclonal antibodies against chicken tropomyosin isoforms: production, characterization, and application. Hybridoma. 1985;4:223-42 pubmed
Lin J, Hegmann T, Lin J. Differential localization of tropomyosin isoforms in cultured nonmuscle cells. J Cell Biol. 1988;107:563-72 pubmed
Hegmann T, Lin J, Lin J. Probing the role of nonmuscle tropomyosin isoforms in intracellular granule movement by microinjection of monoclonal antibodies. J Cell Biol. 1989;109:1141-52 pubmed
Hegmann T, Lin J, Lin J. Motility-dependence of the heterogenous staining of culture cells by a monoclonal anti-tropomyosin antibody. J Cell Biol. 1988;106:385-93 pubmed
产品信息
内部号码 :
6132
名称 :
CGbeta6
Depositor Name :
Lin, J.J.-C.
Depositor Institution :
University of Iowa
Date Deposited :
7/17/09
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
原肌球蛋白, TPM1
抗原物种 :
鸡
宿主物种 :
小鼠
抗体亚型 :
MIgM
Isotype for catalog (legacy) :
IgM
Positive Tested Species Reactivity :
鸡, 人类, 啮齿类
Species Tested (legacy) :
human tropomyosin isoforms 2 and 3 (hTM and hTM3), rodent and chicken tropomyosins
Initial Publication Pubmed ID :
3899907
Collections :
细胞骨架, 人类, 骨骼肌
搜索关键词 :
Lin, J.J.-C., tropomyosin, TPM1, Chicken, MIgM, human/rodent/chicken, TPM1, , AB_10573118, monoclonal, Cytoskeletal elements/skeletal muscle/Human, Immunohistochemistry/Immunofluorescence/Immunoprecipitation/Western Blot
抗原分子量 :
Apparent: 34kDa
基因 :
TPM1
UniProt数据库编号 :
P04268
抗体登记处号码 :
AB_10573118
免疫原 :
纯化鸡砂囊原肌球蛋白
免疫原序列 :
全长蛋白
克隆性 :
单克隆
Myeloma Strain :
NS1
表位定位 :
Yes
Epitope Location or Sequence :
C-terminal end of Human Tm2 and Tm3 (TPM1)
表位定位Pubmed登录号 :
22069507
Recommended Applications :
免疫荧光, 免疫组化, 免疫沉淀, 免疫印迹
Immunoblotting (legacy) :
yes
免疫组化PubMed IDs :
17075344 19209821
免疫荧光PubMed IDs :
7730405 22069507 26147585 26475688 3047141 19209824 16854366 8743945
免疫印迹PubMed IDs :
3899907 2670955 2448313 7730405 8457589 9558279 26147585 26475688 24477237 17075344 3047141 16479376 12415009 21289288
免疫沉淀PubMed IDs :
2670955
其他信息 :
CGbeta6 recognizes the slow-migrating component of gizzard tropomyosin and cross-reacts with chicken embryo fibroblasts tropomyosin, particularly isoforms a, b, 1, and 2, but does not recognize tropomyosin isoforms from striated muscle. Recognizes Human and rat Tm2 and Tm3 (encoded by TPM1) and rat Tm5a (TPM1) [PMID: 22069507].
DSHB增长培养基 :
Iscove's
References (legacy) :
Hybridoma 4, 223-242.; J. Cell Biol. 106, 385-393.; J. Cell Biol. 107, 563-572.; J. Cell Biol. 109, 1141-1152.; Cell Motil. Cytoskel. 26, 248-261.; J. Cell Biol. 129, 697-708.; Gasteroenterology 114, 912-922.; Parasitol. Res. 99, 45-54.; Inflamm. Bowel Dis. 12, 1036-1043.; Adv. Exp. Med. Biol. 644, 201.222.
更多信息或购买 :
Developmental Studies Hybridoma Bank 产品网页
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构，为生命科学研究领域及诊断领域，提供高质量的抗体等产品。