产品简要
公司名称 :
Creative BioMart
产品类型 :
抗体
产品名称 :
Rabbit Anti-Human 5-Hydroxymethylcytosine monoclonal antibody, clone SN347
目录 :
CABT-L1171
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
SN347
应用 :
酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
产品信息
猫 :
CABT-L1171
Proudct Name :
Rabbit Anti-Human 5-Hydroxymethylcytosine monoclonal antibody, clone SN347
简称 :
5-Hydroxymethylcytosine antibody
来源/宿主 :
兔
Common name :
5-Hydroxymethylcytosine
物种 :
人类
共轭标签 :
未共轭
应用 :
酶联免疫吸附测定, 免疫细胞化学, 免疫组化, 免疫沉淀, IF
应用注释 :
Recommended dilution: ELISA: 0.1 - 1 μg/ml ICC: 0.5 - 2 μg/ml IHC: 0.1 - 1 μg/ml IP: 0.2 - 2 μg/ml IF: 0.5 - 2 μg/ml
免疫原 :
BSA-conjugated 5-hydroxymethylcytosine
抗体抗体亚型 :
IgG
储存 :
存放在-20°C, 避免反复冷冻/解冻
靶标 :
5-Hydroxymethylcytosine
物种活性 :
人类
克隆 :
SN347
纯化 :
蛋白质A纯化
BSA :
1% BSA
别称 :
C5H7N3O
格式 :
液体
浓度 :
1毫克/毫升
缓冲液 :
PBS, pH 7.2-7.4, with 1% BSA, 50% glycerol
防腐剂 :
0.09% 叠氮化钠
Warning :
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Introduction :
5-hydroxymethylcytosine (5-hmC) has been recently discovered in mammalian DNA. 5-hmC results from the enzymatic conversion of 5-methylcytosine into 5-hydroxymethylcytosine by the TET family of oxygenases. Initially, the 5-hmC base had been identified in Purkinje neurons, in granule cells and embryonic stem cells where it is present at high levels (up to 0,6% of total nucleotides in Purkinje cells). A recent report indicates that 5-hmC is also abundant in brain tissue, especially in areas that are associated with higher cognitive functions.Early evidence suggests that 5-hmC may represent an intermediate in a new pathway which demethylates DNA, converting 5-mC to cytosine. Although its precise role has still to be shown, recent results indicate, however, that 5-hmC may play important roles distinct from 5-mC. This may open up entirely new perspectives in epigenetic studies.
关键词 :
C5H7N3O
Applicatons :
酶联免疫吸附测定, 免疫细胞化学, 免疫组化, 免疫沉淀, IF
克隆性 :
单克隆
更多信息或购买 :
公司信息
Creative BioMart
Creative Biomart为生物研究、临床研究、分子诊断及生物药物研发等领域，提供高质量的重组蛋白、诊断用抗原抗体、诊断用酶及制药用酶等产品。