抗体

Anti-Androgen Receptor (AR-V7 specific) monoclonal antibody, clone SN8

CABT-BL8504

100微升

单克隆

domestic rabbit

未共轭

SN8

免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀

Anti-Androgen Receptor (AR-V7 specific) monoclonal antibody, clone SN8

雄激素受体抗体

兔

AR

人类

未共轭

IHC, ICC, IP, WB, ChIP, Circulating Tumor Cells

免疫组化(免疫组化):1:500-1:1000稀释;免疫细胞化学(免疫细胞化学):1:100-1:1000稀释;免疫印迹(免疫印迹):1:500-1:1000稀释

A peptide corresponding to AR splice variant 7

IgG

100微升

Stable for 1 Year at -20.0°C from date of receipt

Reacts to androgen receptor splice variant 7 (AR-V7). No cross reactivity with wild type androgen receptor.

人类

SN8

Protein A affinity purified from an animal origin–free culture supernatant

1% BSA

AR; androgen receptor; KD; AIS; TFM; DHTR; SBMA; HYSP1; NR3C4; SMAX1; HUMARA; dihydrotestosterone receptor; androgen nuclear receptor variant 2; nuclear receptor subfamily 3 group C member 4;

液体

50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

0.09% 叠氮化钠

The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

P10275

免疫印迹, 免疫细胞化学/IF, 免疫组化-P, 免疫组化

单克隆