产品简要
公司名称 :
Creative BioMart
产品类型 :
抗体
产品名称 :
Anti-Androgen Receptor (AR-V7 specific) monoclonal antibody, clone SN8
目录 :
CABT-BL8504
规格 :
100微升
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
SN8
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀
更多信息或购买 :
产品信息
猫 :
CABT-BL8504
Proudct Name :
Anti-Androgen Receptor (AR-V7 specific) monoclonal antibody, clone SN8
简称 :
雄激素受体抗体
来源/宿主 :
兔
Common name :
AR
物种 :
人类
共轭标签 :
未共轭
应用 :
IHC, ICC, IP, WB, ChIP, Circulating Tumor Cells
应用注释 :
免疫组化(免疫组化):1:500-1:1000稀释;免疫细胞化学(免疫细胞化学):1:100-1:1000稀释;免疫印迹(免疫印迹):1:500-1:1000稀释
免疫原 :
A peptide corresponding to AR splice variant 7
抗体抗体亚型 :
IgG
规格 :
100微升
储存 :
Stable for 1 Year at -20.0°C from date of receipt
特异性 :
Reacts to androgen receptor splice variant 7 (AR-V7). No cross reactivity with wild type androgen receptor.
物种活性 :
人类
克隆 :
SN8
纯化 :
Protein A affinity purified from an animal origin–free culture supernatant
BSA :
1% BSA
别称 :
AR; androgen receptor; KD; AIS; TFM; DHTR; SBMA; HYSP1; NR3C4; SMAX1; HUMARA; dihydrotestosterone receptor; androgen nuclear receptor variant 2; nuclear receptor subfamily 3 group C member 4;
格式 :
液体
缓冲液 :
50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
防腐剂 :
0.09% 叠氮化钠
Introduction :
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
UniProt数据库编号 :
P10275
Applicatons :
免疫印迹, 免疫细胞化学/IF, 免疫组化-P, 免疫组化
克隆性 :
单克隆
更多信息或购买 :
公司信息
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Creative BioMart
Creative Biomart为生物研究、临床研究、分子诊断及生物药物研发等领域,提供高质量的重组蛋白、诊断用抗原抗体、诊断用酶及制药用酶等产品。