产品简要
公司名称 :
Creative BioMart
产品类型 :
抗体
产品名称 :
小鼠抗MMAF单克隆抗体, 克隆G4C22
目录 :
CABT-B8994
规格 :
100微升, 500微升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
G4C22
应用 :
酶联免疫吸附测定
更多信息或购买 :
产品信息
猫 :
CABT-B8994
Proudct Name :
小鼠抗MMAF单克隆抗体, 克隆G4C22
简称 :
MMAF抗体
来源/宿主 :
小鼠
Common name :
MMAF
共轭标签 :
未共轭
应用 :
酶联免疫吸附测定
应用注释 :
Optimal dilutions for each application to be determined by the researcher. Prepare working dilution immediately before use.
抗体抗体亚型 :
IgG
规格 :
100微升, 500微升
储存 :
For short term storage, store at 4°C up to 6 months from date of opening or thawing. Long time storage is recommended at -20°C. Avoid repeated freeze-thaw cycles.
靶标 :
MMAF
克隆 :
G4C22
纯化 :
Antibody was produced by ascites and then isolated via Protein A/G chromatography
BSA :
1% BSA
别称 :
Monomethyl auristatin F; MMAF;
格式 :
液体
浓度 :
1毫克/毫升
缓冲液 :
PBS
防腐剂 :
0.02% 叠氮化钠
Ship :
干冰
Warning :
For research use only.
Introduction :
MMAF is a synthetic antineoplastic agent. Monomethyl auristatin F (MMAF) is an antitubulin agent that inhibits cell division by blocking the polymerization of tubulin. Because of MMAF is highly toxic, it cannot be used as a drug itself. MMAF induces potent antitumor effects when conjugated via protease cleavable linkers to a monoclonal antibody targeting internalizing, tumor-specific cell surface antigens. The linker to the monoclonal antibody is stable in extracellular fluid, but is cleaved by cathepsin once the conjugate has entered a tumor cell, thus activating the anti-mitotic mechanism.
关键词 :
Monomethyl auristatin F;MMAF;
Official Symbol :
Monomethyl auristatin F
产品简列 :
小鼠抗MMAF单克隆抗体
Applicatons :
酶联免疫吸附测定
克隆性 :
单克隆
更多信息或购买 :
公司信息
Creative BioMart
Creative Biomart为生物研究、临床研究、分子诊断及生物药物研发等领域，提供高质量的重组蛋白、诊断用抗原抗体、诊断用酶及制药用酶等产品。