产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
A20/TNFAIP3(D13H3)兔单克隆抗体
目录 :
5630
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
D13H3
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫沉淀, 流式细胞仪, 免疫印迹基因敲除验证
文章摘录数: 18
出版应用/物种/样本/稀释参考文献
  • 免疫印迹基因敲除验证; 小鼠; 图 s1a
  • 免疫印迹; 小鼠; 图 6b
  • 免疫印迹; 人类; 图 s6b
Rusu I, Mennillo E, Bain J, Li Z, Sun X, Ly K, et al. Microbial signals, MyD88, and lymphotoxin drive TNF-independent intestinal epithelial tissue damage. J Clin Invest. 2022;132: pubmed 出版商
  • 免疫印迹; 小鼠; 图 2e
Li X, Zhang M, Huang X, Liang W, Li G, Lu X, et al. Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners. Nat Commun. 2020;11:6364 pubmed 出版商
  • 免疫沉淀; 人类; 图 2c
  • 免疫印迹; 人类; 1:1000; 图 2c, 6a
Feng Y, Zhang Y, Cai Y, Liu R, Lu M, Li T, et al. A20 targets PFKL and glycolysis to inhibit the progression of hepatocellular carcinoma. Cell Death Dis. 2020;11:89 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5e
Seeholzer T, Kurz S, Schlauderer F, Woods S, Gehring T, Widmann S, et al. BCL10-CARD11 Fusion Mimics an Active CARD11 Seed That Triggers Constitutive BCL10 Oligomerization and Lymphocyte Activation. Front Immunol. 2018;9:2695 pubmed 出版商
  • 免疫印迹; 人类; 图 5f
Bi E, Li R, Bover L, Li H, Su P, Ma X, et al. E-cadherin expression on multiple myeloma cells activates tumor-promoting properties in plasmacytoid DCs. J Clin Invest. 2018;128:4821-4831 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1b
Siegmund D, Ehrenschwender M, Wajant H. TNFR2 unlocks a RIPK1 kinase activity-dependent mode of proinflammatory TNFR1 signaling. Cell Death Dis. 2018;9:921 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2c
  • 免疫印迹; 人类; 1:1000; 图 2c
Sokhi U, Liber M, Frye L, Park S, Kang K, Pannellini T, et al. Dissection and function of autoimmunity-associated TNFAIP3 (A20) gene enhancers in humanized mouse models. Nat Commun. 2018;9:658 pubmed 出版商
  • 免疫印迹; 人类; 图 1d
Song X, Yao Z, Yang J, Zhang Z, Deng Y, Li M, et al. HCV core protein binds to gC1qR to induce A20 expression and inhibit cytokine production through MAPKs and NF-κB signaling pathways. Oncotarget. 2016;7:33796-808 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Ai L, Xu Q, Wu C, Wang X, Chen Z, Su D, et al. A20 Attenuates FFAs-induced Lipid Accumulation in Nonalcoholic Steatohepatitis. Int J Biol Sci. 2015;11:1436-46 pubmed 出版商
  • 流式细胞仪; 人类; 图 4a
Guzmán E, Maers K, Roberts J, Kemami Wangun H, Harmody D, Wright A. The marine natural product microsclerodermin A is a novel inhibitor of the nuclear factor kappa B and induces apoptosis in pancreatic cancer cells. Invest New Drugs. 2015;33:86-94 pubmed 出版商
Kreckel J, Anany M, Siegmund D, Wajant H. TRAF2 Controls Death Receptor-Induced Caspase-8 Processing and Facilitates Proinflammatory Signaling. Front Immunol. 2019;10:2024 pubmed 出版商
Lee I, Lim J, Cho H, Kim E, Kim Y, Oh H, et al. MST1 Negatively Regulates TNFα-Induced NF-κB Signaling through Modulating LUBAC Activity. Mol Cell. 2019;73:1138-1149.e6 pubmed 出版商
Li Y, Mooney E, Holden S, Xia X, Cohen D, Walsh S, et al. A20 Orchestrates Inflammatory Response in the Oral Mucosa through Restraining NF-κB Activity. J Immunol. 2019;202:2044-2056 pubmed 出版商
Essig K, Kronbeck N, Guimaraes J, Lohs C, Schlundt A, Hoffmann A, et al. Roquin targets mRNAs in a 3'-UTR-specific manner by different modes of regulation. Nat Commun. 2018;9:3810 pubmed 出版商
Dalet A, Argüello R, Combes A, Spinelli L, Jaeger S, Fallet M, et al. Protein synthesis inhibition and GADD34 control IFN-β heterogeneous expression in response to dsRNA. EMBO J. 2017;36:761-782 pubmed 出版商
Zhou Q, Wang H, Schwartz D, Stoffels M, Park Y, Zhang Y, et al. Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease. Nat Genet. 2016;48:67-73 pubmed 出版商
Shao L, Oshima S, Duong B, Advincula R, Barrera J, Malynn B, et al. A20 restricts wnt signaling in intestinal epithelial cells and suppresses colon carcinogenesis. PLoS ONE. 2013;8:e62223 pubmed 出版商
Tokunaga F, Nishimasu H, Ishitani R, Goto E, Noguchi T, Mio K, et al. Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-?B regulation. EMBO J. 2012;31:3856-70 pubmed 出版商
产品信息
SKU号 :
5630S
产品名称 :
A20/TNFAIP3(D13H3)兔单克隆抗体
规格 :
100微升
Price-(USD) :
235美元
物种x :
H, M, R, Mk
应用 :
免疫沉淀
产品种类 :
免疫学和炎症
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
82
宿主 :
靶标 :
TNFAIP3
最初蛋白 :
TNFAIP3
别名 :
A20,MGC104522,MGC138687,MGC138688,OTU domain-containing protein 7C,OTUD7C,Putative DNA-binding protein A20,TNAP3,TNF alpha-induced protein 3,TNFA1P2,TNFAIP3,Tumor necrosis factor alpha-induced protein 3,Zinc finger protein A20,tumor necrosis factor inducible protein A20,tumor necrosis factor, alpha-induced protein 3
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。