抗体

抗TRX1 TXN兔单克隆抗体

M01219

100微升

315美元

单克隆

domestic rabbit

未共轭

AOGC-20

免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀

抗TRX1 TXN兔单克隆抗体

315美元

100微升

单克隆

AOGC-20

兔

人类

免疫沉淀, IF, 免疫组化, 免疫细胞化学, 免疫印迹

免疫印迹1:500-1:2000。 免疫组化1:50-1:200。 免疫细胞化学/IF 1:50-1:200。 免疫沉淀1:50

Boster Bio Anti-TRX1 TXN Rabbit Monoclonal Antibody catalog # M01219. Tested in IP, IF, IHC, ICC, WB applications. This antibody reacts with Human.

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

TXN

P10599

A synthesized peptide derived from human TRX1

液体

兔IgG在磷酸盐缓冲液, pH值7.4, 150mM氯化钠, 0.02% 叠氮化钠和50% 甘油, 0.4 0.5毫克/毫升BSA

亲和色谱

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

硫氧还蛋白

Thioredoxin; Trx; ATL-derived factor; ADF; Surface-associated sulphydryl protein; SASP; TXN; TRDX, TRX, TRX1;

11737分子量

Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.

Nucleus. Cytoplasm. Secreted. Secreted by a leaderless secretory pathway. Predominantly in the cytoplasm in non irradiated cells. Radiation induces translocation of TRX from the cytoplasm to the nucleus.

Cancer, Cell Biology, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Oxidative Stress, Pathways And Processes, Redox Metabolism, Signal Transduction