抗体

Anti-CD63 (Late Endosomes Marker) Monoclonal Antibody

M01080

100 ug/vial

440美元

单克隆

小鼠

未共轭

MX-49.129.5

Anti-CD63 (Late Endosomes Marker) Monoclonal Antibody

440美元

100 ug/vial

单克隆

MX-49.129.5

小鼠

人类, 小鼠

流式细胞仪

User need to optimize the dilution ratio for this antibody

Boster Bio Anti-CD63 (Late Endosomes Marker) Monoclonal Antibody catalog # M01080. Tested in Flow Cytometry applications. This antibody reacts with Human, Mouse.

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

CD63

P08962

全长CD63人的起源

液体

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

蛋白质A/G

IgG1, kappa

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

CD63抗原

CD63 antigen; Granulophysin; Lysosomal-associated membrane protein 3; LAMP-3; Melanoma-associated antigen ME491; OMA81H; Ocular melanoma-associated antigen; Tetraspanin-30; Tspan-30; CD63; CD63; MLA1, TSPAN30;

25637分子量

Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.

Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Endosome, multivesicular body. Melanosome. Also found in Weibel-Palade bodies of endothelial cells. Located in platelet dense granules. Detected in a subset of pre-melanosomes. Detected on intralumenal vesicles (ILVs) within multivesicular bodies.

Detected in platelets (at protein level). Dysplastic nevi, radial growth phase primary melanomas, hematopoietic cells, tissue macrophages.

Cancer, Cardiovascular, Cell Adhesion, Cell Type Markers, Immunology, Invasion/Microenvironment, Platelets, Tags & Cell Markers, Tumor Antigens, Tumor Associated, Tumor Biomarkers