抗S100钙结合蛋白B(星形胶质细胞和黑色素瘤标记)单克隆抗体 | 武汉博士德生物工程有限公司 M00979 产品信息

产品简要

公司名称 :

武汉博士德生物工程有限公司

产品类型 :

抗体

产品名称 :

抗S100钙结合蛋白B(星形胶质细胞和黑色素瘤标记)单克隆抗体

M00979

规格 :

100 ug/vial

价格 :

440美元

克隆性 :

单克隆

宿主 :

小鼠

共轭标签 :

未共轭

克隆名称 :

SH-B1

反应物种 :

人类

应用 :

免疫组化

更多信息或购买 :

武汉博士德生物工程有限公司产品网页

产品信息

SKU号 :

M00979

产品名称 :

抗S100钙结合蛋白B(星形胶质细胞和黑色素瘤标记)单克隆抗体

价格 :

440美元

规格 :

100 ug/vial

克隆性 :

单克隆

克隆编号 :

SH-B1

宿主 :

小鼠

反应物种 :

201, 牛, 大鼠, 兔, 人类

应用(s) :

免疫组化

应用细节 :

免疫荧光(1-2微克/毫升)

描述 :

Boster Bio Anti-S100B (Astrocyte and Melanoma Marker) Monoclonal Antibody catalog # M00979. Tested in IHC applications. This antibody reacts with Bovine, Human, Rabbit, Rat.

浓度 :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

基因名称 :

S100B

UniProt数据库编号 :

P04271

免疫原 :

纯化牛大脑S100蛋白质

形式 :

液体

Contents :

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

纯化 :

蛋白质A/G

抗体亚型 :

IgG1, kappa

储存 :

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

基因全称 :

蛋白S100-B

同义词 :

蛋白S100-B;S-100蛋白乙链;S-100蛋白亚基乙;S100钙结合蛋白B;S100钙结合蛋白B;

分子量 :

10713分子量

Protein Function :

Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

Subcellular Localization :

Cytoplasm. Nucleus.

组织特异性 :

Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.

研究种类 :

Cell Biology, Cell Cycle, Cell Differentiation, Epigenetics and Nuclear Signaling, Neural Stem Cells, Stem Cells

更多信息或购买 :

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公司信息