抗体

抗LTBR小鼠单克隆抗体[克隆ID:OTI3G10]

M00942

100微升

494美元

单克隆

小鼠

未共轭

单克隆

抗LTBR小鼠单克隆抗体[克隆ID:OTI3G10]

494美元

100微升

单克隆

小鼠

人类

免疫印迹

抗LTBR小鼠单克隆抗体[克隆ID:OTI3G10]

1毫克/毫升

LTBR

Human recombinant protein fragment corresponding to amino acids 31-227 of human LTBR (NP_002333) produced in E.coli.

PBS(pH值7.3)含1% BSA, 50% 甘油和0.02% 叠氮化钠

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

IgG1

Store at -20°C as received.

52842

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1- (2,5- dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca (2+) ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.