产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
ELISA/assay
产品名称 :
Mouse PDGF-CC ELISA Kit PicoKine®
目录 :
EK1854
规格 :
96 wells/kit, with removable strips.
价格 :
369美元
更多信息或购买 :
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Mouse PDGF-CC PicoKine ELISA Kit Standard Curve
产品信息
SKU号 :
EK1854
产品名称 :
Mouse PDGF-CC ELISA Kit PicoKine®
规格 :
96 wells/kit, with removable strips.
价格 :
369美元
描述 :
Mouse PDGF-CC ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Pdgfc in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.
反应物种 :
小鼠
应用 :
酶联免疫吸附测定
基因名称 :
Pdgfc
UniProt数据库编号 :
Q8CI19
免疫原 :
Expression system for standard: E.coli; Immunogen sequence: V235-G345
交叉活性 :
There is no detectable cross-reactivity with other relevant proteins.
试验范围 :
15.6 pg/ml - 1,000 pg/ml
敏感性 :
<10 pg/ml
样品类型 :
cell culture supernatants, serum and plasma (heparin, EDTA)
Capture/Detection Antibodies :
a单克隆抗体来自大鼠, a生物素多克隆抗体来自山羊
储存 :
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
基因全称 :
platelet-derived growth factor, C polypeptide
同义词 :
Platelet-derived growth factor C; PDGF-C; Fallotein; Spinal cord-derived growth factor; SCDGF; VEGF-E; Platelet-derived growth factor C, latent form; PDGFC latent form; Platelet-derived growth factor C, receptor-binding form; PDGFC receptor-binding form; Pdgfc; Scdgf
Protein Function :
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen and chemoattractant for cells of mesenchymal origin. Required for normal skeleton formation during embryonic development, especially for normal development of the craniofacial skeleton and for normal development of the palate. Required for normal skin morphogenesis during embryonic development. Plays an important role in wound healing, where it appears to be involved in three stages: inflammation, proliferation and remodeling. Plays an important role in angiogenesis and blood vessel development. Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs. The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the maintenance of the latency of the PDGF domain. In the nucleus, PDGFC seems to have additional function.
Subcellular Localization :
Cell membrane. Secreted. Nucleus. Cytosol. Cytoplasmic granule.
组织特异性 :
Mainly expressed in kidney, testis, liver, heart and brain (at protein level). Highly expressed in airway epithelium, interstitial cells and alveolar macrophages in the lung of mice overexpressing IL13. Expressed in the ovaries.
背景 :
Platelet-derived growth factor C, also known as PDGF-C, is a 345-amino acid protein that in humans is encoded by the PDGFC gene. It is mapped to 3; 3 E3. Platelet-derived growth factors are important in connective tissue growth, survival and function, and consist of disulphide-linked dimers involving two polypeptide chains, PDGF-A and PDGF-B. PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique two-domain structure and expression pattern. PDGF-C was not previously identified with PDGF-A and PDGF-B, possibly because it may be that it is synthesized and secreted as a latent growth factor, requiring proteolytic removal of the N-terminal CUB domain for receptor binding and activation.
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公司信息
![logo](http://aws.labome.com/img/2506.png)
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn925.485.4527
公司总部: 美国
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