Anti-CLPB Antibody Picoband™ | 武汉博士德生物工程有限公司 A02912-2 产品信息

产品简要

公司名称 :

武汉博士德生物工程有限公司

产品类型 :

抗体

产品名称 :

Anti-CLPB Antibody Picoband™

A02912-2

规格 :

100µg/vial

价格 :

315美元

克隆性 :

多克隆

宿主 :

domestic rabbit

共轭标签 :

未共轭

克隆名称 :

多克隆

反应物种 :

人类

应用 :

免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片

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产品信息

SKU号 :

A02912-2

产品名称 :

Anti-CLPB Antibody Picoband™

价格 :

315美元

规格 :

100µg/vial

克隆性 :

多克隆

宿主 :

兔

反应物种 :

Human, Monkey, Mouse, Rat

应用(s) :

免疫印迹, 免疫组化-P, 免疫细胞化学, IF, 流式细胞仪, 酶联免疫吸附测定

应用细节 :

Western blot, 0.25-0.5µg/ml, Human, Mouse, Rat, Monkey. Immunohistochemistry (Paraffin-embedded Section), 0.5-1µg/ml, Human. Immunocytochemistry/Immunofluorescence, 4µg/ml, Human. Flow Cytometry, 1-3μg/1x10^6 cells, Human. Direct ELISA, 0.1-0.5µg/ml, Human.

描述 :

Boster Bio Anti-CLPB Antibody Picoband™ catalog # A02912-2. Tested in ELISA, Flow Cytometry, IF, IHC-P, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat.

浓度 :

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

基因名称 :

CLPB

UniProt数据库编号 :

Q9H078

免疫原 :

E.coli-derived human CLPB recombinant protein (Position: Q438-I707).

形式 :

冻干

Contents :

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

纯化 :

免疫原亲和纯化

储存 :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

重组 :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

基因全称 :

C-C motif chemokine 5

同义词 :

C-C motif chemokine 5; EoCP; Eosinophil chemotactic cytokine; SIS-delta; Small-inducible cytokine A5; T cell-specific protein P228; TCP228; T-cell-specific protein RANTES; RANTES (3-68); RANTES (4-68); CCL5; D17S136E, SCYA5;

蛋白名 :

C-C motif chemokine 5

分子量 :

9990分子量

Protein Function :

Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES (3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1- infection. The second processed form RANTES (4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES (1- 68) and RANTES (3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils (PubMed:16791620, PubMed:1380064, PubMed:8525373, PubMed:9516414, PubMed:15923218). May also be an agonist of the G protein-coupled receptor GPR75, stimulating inositol trisphosphate production and calcium mobilization through its activation. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells (PubMed:23979485).

Subcellular Localization :

Secreted.

组织特异性 :

Expressed in the follicular fluid (at protein level). T-cell and macrophage specific.

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