抗体

Anti-Caveolin-2/CAV2 Antibody Picoband™

A01574

100µg/vial

315美元

多克隆

domestic rabbit

未共轭

多克隆

免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片

Anti-Caveolin-2/CAV2 Antibody Picoband™

315美元

100µg/vial

多克隆

兔

Human, Monkey, Mouse, Rat

免疫印迹, 免疫组化-P, 免疫细胞化学, IF, 流式细胞仪, 酶联免疫吸附测定

Western blot, 0.1-0.25µg/ml, Human, Mouse, Monkey, Rat. Immunohistochemistry (Paraffin-embedded Section), 0.5-1µg/ml, Human, Mouse, Rat. Immunocytochemistry/Immunofluorescence, 4µg/ml, Human. Immunofluorescence, 4µg/ml, Human. Flow Cytometry, 1-3μg/1x10^6 cells, Human. Direct ELISA, 0.1-0.5µg/ml, Human.

Boster Bio Anti-Caveolin-2/CAV2 Antibody Picoband™ catalog # A01574. Tested in ELISA, Flow Cytometry, IF, IHC-P, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

CAV2

P51636

E.coli-derived human Caveolin-2/CAV2 recombinant protein (Position: L3-D162).

冻干

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

免疫原亲和纯化

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Tyrosine-protein kinase Mer

Tyrosine-protein kinase Mer; 2.7.10.1; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK; MERTK; MER;

Tyrosine-protein kinase Mer

110249分子量

Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including LGALS3, TUB, TULP1 or GAS6. Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis). Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1. MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis. Plays also an important role in inhibition of Toll- like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.

Membrane ; Single-pass type I membrane protein.

Not expressed in normal B- and T-lymphocytes but is expressed in numerous neoplastic B- and T-cell lines. Highly expressed in testis, ovary, prostate, lung, and kidney, with lower expression in spleen, small intestine, colon, and liver.