产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
Purified (azide-free) anti-β-Amyloid, 1-42
目录 :
805509
规格 :
50微升
价格 :
147美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
12F4
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 21
参考文献
Olah M, Menon V, Habib N, Taga M, Ma Y, Yung C, et al. Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer's disease. Nat Commun. 2020;11:6129 pubmed 出版商
Li K, Jiang Y, Li G, Liu T, Yang Z. Novel Multitarget Directed Tacrine Hybrids as Anti-Alzheimer's Compounds Improved Synaptic Plasticity and Cognitive Impairment in APP/PS1 Transgenic Mice. ACS Chem Neurosci. 2020;11:4316-4328 pubmed 出版商
Barbato C, Giacovazzo G, Albiero F, Scardigli R, Scopa C, Ciotti M, et al. Cognitive Decline and Modulation of Alzheimer's Disease-Related Genes After Inhibition of MicroRNA-101 in Mouse Hippocampal Neurons. Mol Neurobiol. 2020;57:3183-3194 pubmed 出版商
Shi H, Koronyo Y, Rentsendorj A, Regis G, Sheyn J, Fuchs D, et al. Identification of early pericyte loss and vascular amyloidosis in Alzheimer's disease retina. Acta Neuropathol. 2020;139:813-836 pubmed 出版商
Kim K, Kim M, Kim D, Kim S, Park S, Park C. Clinically accurate diagnosis of Alzheimer's disease via multiplexed sensing of core biomarkers in human plasma. Nat Commun. 2020;11:119 pubmed 出版商
Chan H, Xu D, Ho S, He D, Wong M, Li H. Highly sensitive quantification of Alzheimer's disease biomarkers by aptamer-assisted amplification. Theranostics. 2019;9:2939-2949 pubmed 出版商
Ruiz Riquelme A, Lau H, Stuart E, Goczi A, Wang Z, Schmitt Ulms G, et al. Prion-like propagation of β-amyloid aggregates in the absence of APP overexpression. Acta Neuropathol Commun. 2018;6:26 pubmed 出版商
Lee C, Daggett A, Gu X, Jiang L, Langfelder P, Li X, et al. Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models. Neuron. 2018;97:1032-1048.e5 pubmed 出版商
Kommaddi R, Das D, Karunakaran S, Nanguneri S, Bapat D, Ray A, et al. Aβ mediates F-actin disassembly in dendritic spines leading to cognitive deficits in Alzheimer's disease. J Neurosci. 2018;38:1085-1099 pubmed 出版商
Kim C, Park J, Kong T, Lee S, Seo K, Choi Y, et al. Double-Injected Human Stem Cells Enhance Rehabilitation in TBI Mice Via Modulation of Survival and Inflammation. Mol Neurobiol. 2018;55:4870-4884 pubmed 出版商
Moreno F, Indakoetxea B, Barandiaran M, Caballero M, Gorostidi A, Calafell F, et al. The unexpected co-occurrence of GRN and MAPT p.A152T in Basque families: Clinical and pathological characteristics. PLoS ONE. 2017;12:e0178093 pubmed 出版商
Ahmad F, Singh K, Das D, Gowaikar R, Shaw E, Ramachandran A, et al. Reactive Oxygen Species-Mediated Loss of Synaptic Akt1 Signaling Leads to Deficient Activity-Dependent Protein Translation Early in Alzheimer's Disease. Antioxid Redox Signal. 2017;27:1269-1280 pubmed 出版商
Augé E, Cabezón I, Pelegri C, Vilaplana J. New perspectives on corpora amylacea in the human brain. Sci Rep. 2017;7:41807 pubmed 出版商
Eimer W, Vassar R. Neuron loss in the 5XFAD mouse model of Alzheimer's disease correlates with intraneuronal A?42 accumulation and Caspase-3 activation. Mol Neurodegener. 2013;8:2 pubmed 出版商
Helwig M, Hoshino A, Berridge C, Lee S, Lorenzen N, Otzen D, et al. The neuroendocrine protein 7B2 suppresses the aggregation of neurodegenerative disease-related proteins. J Biol Chem. 2013;288:1114-24 pubmed 出版商
Ohmi K, Zhao H, Neufeld E. Defects in the medial entorhinal cortex and dentate gyrus in the mouse model of Sanfilippo syndrome type B. PLoS ONE. 2011;6:e27461 pubmed 出版商
Maheshwari M, Roberts J, Desutter B, Duong K, Tingling J, Fawver J, et al. Hydralazine modifies A? fibril formation and prevents modification by lipids in vitro. Biochemistry. 2010;49:10371-80 pubmed 出版商
Vingtdeux V, Chandakkar P, Zhao H, d Abramo C, Davies P, Marambaud P. Novel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-? peptide degradation. FASEB J. 2011;25:219-31 pubmed 出版商
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Sudol K, Mastrangelo M, Narrow W, Frazer M, Levites Y, Golde T, et al. Generating differentially targeted amyloid-beta specific intrabodies as a passive vaccination strategy for Alzheimer's disease. Mol Ther. 2009;17:2031-40 pubmed 出版商
产品信息
抗原 :
乙淀粉样蛋白1-42
Apps. Abbrev. :
IHC-P, Direct ELISA, WB, IHC-F
目录 :
805509
克隆 :
12F4
产品 :
Purified (azide-free) anti-β-Amyloid, 1-42
抗体亚型 :
Mouse IgG1, κ
其他名称 :
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, Amyloid beta A4 protein, preA4, protease nexin-II, peptidase nexin-II, beta-amyloid peptide, alzheimer disease amyloid protein, cerebral vascular amyloid peptide, APP, Amyloid Precursor Protein
规格 :
50微升
价格(美元) :
147美元
反应物种 :
人类, 小鼠, 大鼠
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
PUREAF
应用注释 :
This antibody is effective in immunoblotting (WB), immunohistochemistry (IHC), and ELISA.This antibody is reactive to the C-terminus of beta amyloid and is specific for the isoform ending at the 42nd amino acid.Additional reported applications (for the relevant formats) includes: immunohistochemical staining of paraformaldehyde-fixed frozen sections^6 and ELISA^3,4,5.;
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。