Babco, Signet, Sternberger Monoclonals, Senetek, Covance

抗体

HRP抗甲I幽灵蛋白

803106

100微克

323美元

单克隆

小鼠

HRP

17C7

人类, 小鼠, 大鼠

免疫印迹

803106

17C7

HRP抗甲I幽灵蛋白

Mouse IgG1, κ

EL2, SPTA1, Spectrin alpha chain, erythrocyte, alpha-I spectrin, erythroid alpha-spectrin

100微克

323美元

人类, 小鼠, 大鼠

单克隆

小鼠

HRP

Clone 17C7 is developed against the alpha I spectrin SH3 domain (Xu et al ., 2000) 2 .

This antibody is effective in Western Blotting (WB). Additional reported applications include immunocytochemistry^1, 2.Clone 17C7 is a specific marker for human, rat and mouse alpha I spectrin. It reacts with erythroid spectrin in red blood cells and in cerebellum. It does not crossreact with alpha II (nonerythroid) spectrin SH3 domain or recombinant human fodrin SH3 domain. In cerebellar cell cultures, clone 17C7 labels cell bodies consistent with localization of erythroid spectrin. In NIH 3T3 cells, clone 17C7 reacts with a 280 kDa protein which is a candidate marker of endocytic vesicles called macropinosomes^1, 2.This antibody was developed against a recombinant alpha I spectrin (erythroid spectrin) SH3 domain.;