Babco, Signet, Sternberger Monoclonals, Senetek, Covance

抗体

Biotin anti-human CD172a/b (SIRPα/β)

323804

100微克

211美元

单克隆

小鼠

生物素

SE5A5

FC

323804

SE5A5

Biotin anti-human CD172a/b (SIRPα/β)

Mouse IgG1, κ

SIRPa, SIRPb, SIRPalpha/beta, BIT, SHPS1, MFR, P84, PTPNS1, CD172 antigen-like family member A, CD172 antigen-like family member B

100微克

211美元

人类

单克隆

小鼠

生物素

NIH-3T3/hu-SIRPα cell line

Clone SE5A5 recognizes a common epitope on SIRPa (90 kD) and SIRPß (50 kD)^3. A high degree of homology has been found between SIRP family isoforms alpha and beta at the level of extracellular domains. Consequently, many anti SIRP antibody clones, such as SE5A5, have been reported to cross react with several SIRP isoforms^1,4,5. It reacts with CD172a and has weak cross-reaction with CD172b. This antibody is able to block the binding of SIRPa (SIRPa1 and SIRPa2) to CD47^1,6.;