大鼠抗髓磷脂碱蛋白(aa82-87) | 伯乐（Bio-Rad）公司 MCA409S 产品信息

产品简要

公司名称 :

伯乐（Bio-Rad）公司

其他品牌 :

Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology

产品类型 :

抗体

产品名称 :

大鼠抗髓磷脂碱蛋白(aa82-87)

MCA409S

规格 :

2毫升

价格 :

493美元

克隆性 :

单克隆

宿主 :

大鼠

共轭标签 :

未共轭

克隆名称 :

反应物种 :

人类, 小鼠, 大鼠, 牛, pigs

应用 :

免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片

更多信息或购买 :

伯乐（Bio-Rad）公司产品网页

文章摘录数: 46

出版应用/物种/样本/稀释	参考文献
免疫细胞化学; 小鼠; 1:50; 图 1b	Bauch J, Faissner A. The Extracellular Matrix Proteins Tenascin-C and Tenascin-R Retard Oligodendrocyte Precursor Maturation and Myelin Regeneration in a Cuprizone-Induced Long-Term Demyelination Animal Model. Cells. 2022;11: pubmed 出版商
免疫组化-冰冻切片; 小鼠; 1:50; 图 6a	Bauch J, Ort S, Ulc A, Faissner A. Tenascins Interfere With Remyelination in an Ex Vivo Cerebellar Explant Model of Demyelination. Front Cell Dev Biol. 2022;10:819967 pubmed 出版商
免疫组化-冰冻切片; 小鼠; 1:500; 图 1w, s1k 免疫细胞化学; 大鼠; 1:500; 图 2i	Aberle T, Piefke S, Hillg xe4 rtner S, Tamm E, Wegner M, K xfc spert M. Transcription factor Zfp276 drives oligodendroglial differentiation and myelination by switching off the progenitor cell program. Nucleic Acids Res. 2022;50:1951-1968 pubmed 出版商
免疫细胞化学; 大鼠; 1:500; 图 e6c	Dorrier C, Aran D, Haenelt E, Sheehy R, Hoi K, Pintarić L, et al. CNS fibroblasts form a fibrotic scar in response to immune cell infiltration. Nat Neurosci. 2021;24:234-244 pubmed 出版商
免疫组化-冰冻切片; 小鼠; 1:500; 图 e5m	Paredes I, Vieira J, Shah B, Ramunno C, Dyckow J, Adler H, et al. Oligodendrocyte precursor cell specification is regulated by bidirectional neural progenitor-endothelial cell crosstalk. Nat Neurosci. 2021;24:478-488 pubmed 出版商
免疫组化; 小鼠; 1:250; 图 7a	Wiemann S, Reinhard J, Reinehr S, Cibir Z, Joachim S, Faissner A. Loss of the Extracellular Matrix Molecule Tenascin-C Leads to Absence of Reactive Gliosis and Promotes Anti-inflammatory Cytokine Expression in an Autoimmune Glaucoma Mouse Model. Front Immunol. 2020;11:566279 pubmed 出版商
免疫印迹; 小鼠; 1:300; 图 3h, 3i, 3l, 3m	Wüst H, Wegener A, Fröb F, Hartwig A, Wegwitz F, Kari V, et al. Egr2-guided histone H2B monoubiquitination is required for peripheral nervous system myelination. Nucleic Acids Res. 2020;48:8959-8976 pubmed 出版商
免疫组化; 大鼠; 1:250; 图 4g	Werkman I, Sikkema A, Versluijs J, Qin J, de Boer P, Baron W. TLR3 agonists induce fibronectin aggregation by activated astrocytes: a role of pro-inflammatory cytokines and fibronectin splice variants. Sci Rep. 2020;10:532 pubmed 出版商
免疫印迹; 小鼠; 1:10,000; 图 7c	Schäfer I, Kaisler J, Scheller A, Kirchhoff F, Haghikia A, Faissner A. Conditional Deletion of LRP1 Leads to Progressive Loss of Recombined NG2-Expressing Oligodendrocyte Precursor Cells in a Novel Mouse Model. Cells. 2019;8: pubmed 出版商
免疫细胞化学; 大鼠; 1:500; 图 1a	Neumann B, Baror R, Zhao C, SEGEL M, Dietmann S, Rawji K, et al. Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells. Cell Stem Cell. 2019;25:473-485.e8 pubmed 出版商
免疫细胞化学; 小鼠; 1:100; 图 2a	SEGEL M, Neumann B, Hill M, Weber I, Viscomi C, Zhao C, et al. Niche stiffness underlies the ageing of central nervous system progenitor cells. Nature. 2019;573:130-134 pubmed 出版商
免疫组化; pigs ; 1:200; 图 s11a	Vrselja Z, Daniele S, Silbereis J, Talpo F, Morozov Y, Sousa A, et al. Restoration of brain circulation and cellular functions hours post-mortem. Nature. 2019;568:336-343 pubmed 出版商
免疫印迹; 小鼠; 1:200; 图 2c	Gerber D, Ghidinelli M, Tinelli E, Somandin C, Gerber J, Pereira J, et al. Schwann cells, but not Oligodendrocytes, Depend Strictly on Dynamin 2 Function. elife. 2019;8: pubmed 出版商
免疫组化; 小鼠; 1:200; 图 1d	Montani L, Pereira J, Norrmen C, Pohl H, Tinelli E, Trötzmüller M, et al. De novo fatty acid synthesis by Schwann cells is essential for peripheral nervous system myelination. J Cell Biol. 2018;217:1353-1368 pubmed 出版商
免疫组化; 人类; 1:200; 图 5b	Sousa A, Zhu Y, Raghanti M, Kitchen R, Onorati M, Tebbenkamp A, et al. Molecular and cellular reorganization of neural circuits in the human lineage. Science. 2017;358:1027-1032 pubmed 出版商
免疫细胞化学; 小鼠; 1:200; 图 1e 免疫组化; 小鼠; 1:200; 图 3a	Medina Rodríguez E, Bribian A, Boyd A, Palomo V, Pastor J, Lagares A, et al. Promoting in vivo remyelination with small molecules: a neuroreparative pharmacological treatment for Multiple Sclerosis. Sci Rep. 2017;7:43545 pubmed 出版商
免疫组化-石蜡切片; 小鼠; 图 1c	Berghoff S, Gerndt N, Winchenbach J, Stumpf S, Hosang L, Odoardi F, et al. Dietary cholesterol promotes repair of demyelinated lesions in the adult brain. Nat Commun. 2017;8:14241 pubmed 出版商
免疫组化-石蜡切片; 小鼠; 1:100; 图 7f	Kemp K, Cerminara N, Hares K, Redondo J, Cook A, Haynes H, et al. Cytokine therapy-mediated neuroprotection in a Friedreich's ataxia mouse model. Ann Neurol. 2017;81:212-226 pubmed 出版商
免疫组化; 小鼠; 1:100; 表 1	Bassett E, Tokarew N, Allemano E, Mazerolle C, Morin K, Mears A, et al. Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation. elife. 2016;5: pubmed 出版商
免疫组化-自由浮动切片; 小鼠; 1:500; 图 s2f	Figueres Oñate M, López Mascaraque L. Adult Olfactory Bulb Interneuron Phenotypes Identified by Targeting Embryonic and Postnatal Neural Progenitors. Front Neurosci. 2016;10:194 pubmed 出版商
免疫细胞化学; 小鼠; 1:200; 图 3 免疫印迹; 小鼠; 1:1000; 图 2	Gökbuget D, Pereira J, Bachofner S, Marchais A, Ciaudo C, Stoffel M, et al. The Lin28/let-7 axis is critical for myelination in the peripheral nervous system. Nat Commun. 2015;6:8584 pubmed 出版商
免疫印迹; 人类; 1:500	Henstridge C, Jackson R, Kim J, Herrmann A, Wright A, Harris S, et al. Post-mortem brain analyses of the Lothian Birth Cohort 1936: extending lifetime cognitive and brain phenotyping to the level of the synapse. Acta Neuropathol Commun. 2015;3:53 pubmed 出版商
免疫细胞化学; 大鼠; 1:50; 图 2 免疫印迹; 大鼠; 1:500; 图 2 免疫印迹; 小鼠; 1:500; 图 1	MÃ¼ller C, Hochhaus N, Fontana X, Luhmann H, White R. SncRNA715 Inhibits Schwann Cell Myelin Basic Protein Synthesis. PLoS ONE. 2015;10:e0136900 pubmed 出版商
免疫细胞化学; 大鼠; 1:500; 图 1 免疫印迹; 大鼠; 1:500; 图 1	Ettle B, Reiprich S, Deusser J, Schlachetzki J, Xiang W, Prots I, et al. Intracellular alpha-synuclein affects early maturation of primary oligodendrocyte progenitor cells. Mol Cell Neurosci. 2014;62:68-78 pubmed 出版商
免疫组化-石蜡切片; pigs ; 1:50	Zhou X, Xie Q, Xi G, Keep R, Hua Y. Brain CD47 expression in a swine model of intracerebral hemorrhage. Brain Res. 2014;1574:70-6 pubmed 出版商
免疫印迹; 小鼠; 1:200	May V, Ettle B, Poehler A, Nuber S, Ubhi K, Rockenstein E, et al. ?-Synuclein impairs oligodendrocyte progenitor maturation in multiple system atrophy. Neurobiol Aging. 2014;35:2357-68 pubmed 出版商
	Mészáros L, Riemenschneider M, Gassner H, Marxreiter F, von Horsten S, Hoffmann A, et al. Human alpha-synuclein overexpressing MBP29 mice mimic functional and structural hallmarks of the cerebellar subtype of multiple system atrophy. Acta Neuropathol Commun. 2021;9:68 pubmed 出版商
	Vaquié A, Sauvain A, Duman M, Nocera G, Egger B, Meyenhofer F, et al. Injured Axons Instruct Schwann Cells to Build Constricting Actin Spheres to Accelerate Axonal Disintegration. Cell Rep. 2019;27:3152-3166.e7 pubmed 出版商
	Manso C, Querol L, Lleixà C, Poncelet M, Mekaouche M, Vallat J, et al. Anti-Neurofascin-155 IgG4 antibodies prevent paranodal complex formation in vivo. J Clin Invest. 2019;129:2222-2236 pubmed 出版商
	Spitzer S, Sitnikov S, Kamen Y, Evans K, Kronenberg Versteeg D, Dietmann S, et al. Oligodendrocyte Progenitor Cells Become Regionally Diverse and Heterogeneous with Age. Neuron. 2019;101:459-471.e5 pubmed 出版商
	Weider M, Starost L, Groll K, Küspert M, Sock E, Wedel M, et al. Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning. Nat Commun. 2018;9:899 pubmed 出版商
	Dillenburg A, Ireland G, Holloway R, Davies C, Evans F, Swire M, et al. Activin receptors regulate the oligodendrocyte lineage in health and disease. Acta Neuropathol. 2018;135:887-906 pubmed 出版商
	Xiao L, Ohayon D, McKenzie I, Sinclair Wilson A, Wright J, Fudge A, et al. Rapid production of new oligodendrocytes is required in the earliest stages of motor-skill learning. Nat Neurosci. 2016;19:1210-1217 pubmed 出版商
	Porcu G, Serone E, De Nardis V, Di Giandomenico D, Lucisano G, Scardapane M, et al. Clobetasol and Halcinonide Act as Smoothened Agonists to Promote Myelin Gene Expression and RxRγ Receptor Activation. PLoS ONE. 2015;10:e0144550 pubmed 出版商
	Henstridge C, Jackson R, Kim J, Herrmann A, Wright A, Harris S, et al. Erratum to: Post-mortem brain analyses of the Lothian Birth Cohort 1936: extending lifetime cognitive and brain phenotyping to the level of the synapse. Acta Neuropathol Commun. 2015;3:83 pubmed 出版商
	Rittchen S, Boyd A, Burns A, Park J, Fahmy T, Metcalfe S, et al. Myelin repair in vivo is increased by targeting oligodendrocyte precursor cells with nanoparticles encapsulating leukaemia inhibitory factor (LIF). Biomaterials. 2015;56:78-85 pubmed 出版商
	Donega M, Giusto E, Cossetti C, Schaeffer J, Pluchino S. Systemic injection of neural stem/progenitor cells in mice with chronic EAE. J Vis Exp. 2014;: pubmed 出版商
	Barateiro A, Domingues H, Fernandes A, Relvas J, Brites D. Rat cerebellar slice cultures exposed to bilirubin evidence reactive gliosis, excitotoxicity and impaired myelinogenesis that is prevented by AMPA and TNF-? inhibitors. Mol Neurobiol. 2014;49:424-39 pubmed 出版商
	Zoupi L, Markoullis K, Kleopa K, Karagogeos D. Alterations of juxtaparanodal domains in two rodent models of CNS demyelination. Glia. 2013;61:1236-49 pubmed 出版商
	Onishi S, Tatsumi Y, Wada K, Yang H, Sugiura Y, Setou M, et al. Sulfatide accumulation in the dystrophic terminals of gracile axonal dystrophy mice: lipid analysis using matrix-assisted laser desorption/ionization imaging mass spectrometry. Med Mol Morphol. 2013;46:160-5 pubmed 出版商
	Barateiro A, Miron V, Santos S, Relvas J, Fernandes A, Ffrench Constant C, et al. Unconjugated bilirubin restricts oligodendrocyte differentiation and axonal myelination. Mol Neurobiol. 2013;47:632-44 pubmed 出版商
	Walczak P, All A, Rumpal N, Gorelik M, Kim H, Maybhate A, et al. Human glial-restricted progenitors survive, proliferate, and preserve electrophysiological function in rats with focal inflammatory spinal cord demyelination. Glia. 2011;59:499-510 pubmed 出版商
	Gordon D, Scolding N. Human mesenchymal stem cell culture for neural transplantation. Methods Mol Biol. 2009;549:103-18 pubmed 出版商
	Walczak P, Kedziorek D, Gilad A, Barnett B, Bulte J. Applicability and limitations of MR tracking of neural stem cells with asymmetric cell division and rapid turnover: the case of the shiverer dysmyelinated mouse brain. Magn Reson Med. 2007;58:261-9 pubmed
	Komatsu M, Waguri S, Chiba T, Murata S, Iwata J, Tanida I, et al. Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature. 2006;441:880-4 pubmed
	Walczak P, Kedziorek D, Gilad A, Lin S, Bulte J. Instant MR labeling of stem cells using magnetoelectroporation. Magn Reson Med. 2005;54:769-74 pubmed

图像

图像 1 :

Published customer image: . Rat anti MBP antibody, clone 12 ( MCA409S ) used to identify rat oligodendrocyte progenitors in vitro by immunofluorescence. Image caption: . Protandim promotes differentiation of primary rat OPCs under oxidative stress. After 2 day de-differentiation of OLs with growth factors bFGF-2 and PDGF-AA, primary rat OPCs were incubated with 30 ug/mL Protandim or vehicle control (EtOH) for 24 h. After removal of medium, cells were subsequently exposed to either control medium or medium with 10 uM tert-butyl hydrogen peroxide (tbH 2 O 2 ) for 5 days. MBP and Olig2 expression were assayed by immunocytochemistry. Data are presented as percentage of control and expressed as the mean SEM of 3 independent experiments. Statistics reflect student s t-test, one-tailed; * p 0.05. From: Lim JL, van der Pol SM, Baron W, McCord JM, de Vries HE, van Horssen J. Protandim Protects Oligodendrocytes against an Oxidative Insult. . Antioxidants (Basel). 2016 Sep 7;5(3). pii: E30 . This is an open access article distributed under the terms of the Creative Commons Attribution License .

产品信息

Entity Type :

单克隆抗体

Entity Category :

抗体

地区 :

(aa82-87)

ProductCode :

MCA409S

描述 :

大鼠抗髓磷脂碱蛋白(aa82-87)

特异性 :

髓磷脂碱蛋白

目标物种 :

牛

宿主 :

大鼠

格式 :

S/N

Isotypes :

IgG2a

应用 :

IF, E, 免疫印迹, R

ApplicationTypes :

西方墨点法, 酶联免疫吸附测定, 免疫荧光, 放射免疫分析法

交叉活性 :

羊, 鸡, 豚鼠, 人类, 哺乳动物, 大鼠, 兔, 小鼠, 猪

克隆 :

规格 :

2毫升

Quantity Value :

规格类型 :

毫升

GO登录号 :

GO:0005886, GO:0005515, GO:0019911, GO:0043209

GOTerms :

bacterial inner membrane,cell membrane,cytoplasmic membrane,GO:0005904,inner endospore membrane,juxtamembrane,plasma membrane lipid bilayer,plasmalemma,alpha-2 macroglobulin receptor-associated protein activity,GO:0045308,protein amino acid binding,protein degradation tagging activity,protein folding chaperone,protein tagging activity,Schwann Cell Myelin Sheath

UniProt数据库登录号 :

P02687

基因 :

髓磷脂碱蛋白

GeneID网址 :

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=618684

出版同义词 :

髓鞘碱性蛋白质

Entity Formats :

S/N

UNSPSC :

41116161

产品形式 :

Tissue Culture Supernatant - liquid

PriceGBP :

352

PriceEUR :

493

PriceUSD :

493美元

PriceCHF :

536

PriceSEK :

5374

PriceNOK :

5400

PriceDKK :

3676

NotForSaleInCountries :

澳大利亚

更多信息或购买 :

伯乐（Bio-Rad）公司产品网页

公司信息

伯乐（Bio-Rad）公司

Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE

antibody_sales_uk@bio-rad.com

https://www.bio-rad-antibodies.com

44-1865-852-700

公司总部: 英国

伯乐（Bio-Rad）公司是世界领先的抗体生产商之一。通过其原名为AbD Serotec公司的专业抗体业务团队，提供超过12,000种抗体及相关试剂，专注于免疫学、肿瘤、兽医研究及细胞生物学等领域。
抗体产品包括细胞凋亡试剂盒，自噬检测试剂，CD分子标记物，标签抗体，免疫学研究抗体，神经科学研究抗体和兽医应用试剂等。
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