Bethyl

抗体

Goat anti-Menin Antibody Biotinylated

A300-106B

100微克

362美元

多克隆

山羊

生物素

免疫印迹, 免疫沉淀

A300-106B

Menin

Goat anti-Menin Antibody Biotinylated

山羊

生物素

0.1 mg. Reconstitute with 100 µl di-H20

100微克

100微克

Antibody was lyophilized in a buffer containing phosphate buffered saline (PBS), 20% trehalose, 0.2% BSA, and 0.09% sodium azide

6 months from date of reconstitution

人类

免疫印迹, 免疫沉淀

2 - 8° C

多克隆

Whole IgG

362美元

MEAI, menin, multiple endocrine neoplasia I, SCG2

www.ncbi.nlm.nih.gov/gene/4221

NP_000235.2

www.ncbi.nlm.nih.gov/protein/NP_000235.2

Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine, Dog, Horse, Guinea pig_10141, Pig, Panda, Orangutan, Monkey, Gorilla and Chimpanzee

一抗

一抗

12352203

Menin is the gene product of the putative tumor suppressor MEN1 associated with the syndrome termed multiple endocrine neoplasia type 1 that may function in the regulation of DNA synthesis or the response to DNA damage. Menin has been shown to interact with JunD, a member of the AP-1 heterodimer and inhibit transcription. Menin has also been shown to interact with Pem, FANCD2, RPA, NMMHCII-A, GFAP, vimentin, Hsp70, NfkappaB proteins, Smads, mSin3A and is part of the MLL2 and MLL1 Set1-like histone H3 K4 methyltransferase complex where it interacts directly with ASH2, Rbbp5, and WDR5. As part of the MLL complexes, menin may mediate its tumor suppressor activity via the regulation of histone methylation of HOX and CDK inhibitor genes. Alternative names for Menin are MEAI, multiple endocrine adenomatosis 1, suppressor Candidate Gene 2, and SCG2.

Between 575 and C-term