产品简要
公司名称 :
碧迪BD
其他品牌 :
Transduction Laboratories, PharMingen, Difco
产品类型 :
抗体
产品名称 :
Ras相关C3肉毒杆菌毒素底物1
目录 :
610650
规格 :
50微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
102/Ras相关C3肉毒杆菌毒素底物1
反应物种 :
人类, 小鼠, 大鼠, ,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-冰冻切片, 其他, 免疫印迹基因敲除验证, 免疫细胞化学基因敲除验证
更多信息或购买 :
文章摘录数: 58
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学基因敲除验证; 小鼠; 1:250; 图 4b
  • 其他; 小鼠; 1:100; 图 3c
O Neil S, Racz B, Brown W, Gao Y, Soderblom E, Yasuda R, et al. Action potential-coupled Rho GTPase signaling drives presynaptic plasticity. elife. 2021;10: pubmed 出版商
  • 免疫印迹; 人类; 1:200; 图 6h
Fayad R, Rojas M, Partisani M, Finetti P, Dib S, Abélanet S, et al. EFA6B regulates a stop signal for collective invasion in breast cancer. Nat Commun. 2021;12:2198 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:2000; 图 4a
Nomura Komoike K, Saitoh F, Fujieda H. Phosphatidylserine recognition and Rac1 activation are required for Müller glia proliferation, gliosis and phagocytosis after retinal injury. Sci Rep. 2020;10:1488 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 e1g
Ramírez C, Hauser A, Vucic E, Bar Sagi D. Plasma membrane V-ATPase controls oncogenic RAS-induced macropinocytosis. Nature. 2019;576:477-481 pubmed 出版商
  • 免疫印迹; 人类; 图 s1a
Ungefroren H, Otterbein H, Fiedler C, Mihara K, Hollenberg M, Gieseler F, et al. RAC1B Suppresses TGF-β1-Dependent Cell Migration in Pancreatic Carcinoma Cells through Inhibition of the TGF-β Type I Receptor ALK5. Cancers (Basel). 2019;11: pubmed 出版商
  • 免疫印迹; 小鼠; 图 6b
Lin C, Zhang Y, Zhang K, Zheng Y, Lu L, Chang H, et al. Fever Promotes T Lymphocyte Trafficking via a Thermal Sensory Pathway Involving Heat Shock Protein 90 and α4 Integrins. Immunity. 2019;50:137-151.e6 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4c
Roy N, MacKay J, Robertson T, Hammer D, Burkhardt J. Crk adaptor proteins mediate actin-dependent T cell migration and mechanosensing induced by the integrin LFA-1. Sci Signal. 2018;11: pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 图 3a
Ge J, Burnier L, Adamopoulou M, Kwa M, Schaks M, Rottner K, et al. RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells. J Biol Chem. 2018;293:9358-9369 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3c
Polacheck W, Kutys M, Yang J, Eyckmans J, Wu Y, Vasavada H, et al. A non-canonical Notch complex regulates adherens junctions and vascular barrier function. Nature. 2017;552:258-262 pubmed 出版商
  • 免疫印迹; 人类; 图 3a
Barbiero I, Peroni D, Tramarin M, Chandola C, Rusconi L, Landsberger N, et al. The neurosteroid pregnenolone reverts microtubule derangement induced by the loss of a functional CDKL5-IQGAP1 complex. Hum Mol Genet. 2017;26:3520-3530 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类; 图 1d
Yoon C, Cho S, Chang K, Park D, Ryeom S, Yoon S. Role of Rac1 Pathway in Epithelial-to-Mesenchymal Transition and Cancer Stem-like Cell Phenotypes in Gastric Adenocarcinoma. Mol Cancer Res. 2017;15:1106-1116 pubmed 出版商
  • 免疫印迹; 人类; 图 1b
Ruhe F, Olling A, Abromeit R, Rataj D, Grieschat M, Zeug A, et al. Overexpression of the Endosomal Anion/Proton Exchanger ClC-5 Increases Cell Susceptibility toward Clostridium difficile Toxins TcdA and TcdB. Front Cell Infect Microbiol. 2017;7:67 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7D
Jeannot P, Nowosad A, Perchey R, Callot C, Bennana E, Katsube T, et al. p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway. elife. 2017;6: pubmed 出版商
  • 免疫印迹; 人类; 图 6a
Eppler F, Quast T, Kolanus W. Dynamin2 controls Rap1 activation and integrin clustering in human T lymphocyte adhesion. PLoS ONE. 2017;12:e0172443 pubmed 出版商
  • 免疫印迹; 大鼠; 图 3c
Lovric S, Gonçalves S, Gee H, Oskouian B, Srinivas H, Choi W, et al. Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency. J Clin Invest. 2017;127:912-928 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6b
Rafiq N, Lieu Z, Jiang T, Yu C, Matsudaira P, Jones G, et al. Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNO. J Cell Biol. 2017;216:181-197 pubmed 出版商
  • 免疫印迹; 人类; 图 s3c
Tao L, Zhang J, Meraner P, Tovaglieri A, Wu X, Gerhard R, et al. Frizzled proteins are colonic epithelial receptors for C. difficile toxin B. Nature. 2016;538:350-355 pubmed 出版商
  • 免疫印迹; 人类; 图 5b
Frank S, Köllmann C, van Lidth de Jeude J, Thiagarajah J, Engelholm L, Frödin M, et al. The focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion. Oncogene. 2017;36:1816-1828 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 s4
Fusté N, Fernández Hernández R, Cemeli T, Mirantes C, Pedraza N, Rafel M, et al. Cytoplasmic cyclin D1 regulates cell invasion and metastasis through the phosphorylation of paxillin. Nat Commun. 2016;7:11581 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3A
Chen L, DeWispelaere A, Dastvan F, Osborne W, Blechner C, Windhorst S, et al. Smooth Muscle-Alpha Actin Inhibits Vascular Smooth Muscle Cell Proliferation and Migration by Inhibiting Rac1 Activity. PLoS ONE. 2016;11:e0155726 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 4
Takenaka N, Nihata Y, Satoh T. Rac1 Activation Caused by Membrane Translocation of a Guanine Nucleotide Exchange Factor in Akt2-Mediated Insulin Signaling in Mouse Skeletal Muscle. PLoS ONE. 2016;11:e0155292 pubmed 出版商
  • 免疫细胞化学; 人类; 图 7
  • 免疫印迹; 人类; 图 7
Marcos Ramiro B, García Weber D, Barroso S, Feito J, Ortega M, Cernuda Morollón E, et al. RhoB controls endothelial barrier recovery by inhibiting Rac1 trafficking to the cell border. J Cell Biol. 2016;213:385-402 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1
Marei H, Carpy A, Woroniuk A, Vennin C, White G, Timpson P, et al. Differential Rac1 signalling by guanine nucleotide exchange factors implicates FLII in regulating Rac1-driven cell migration. Nat Commun. 2016;7:10664 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s3
Giampietro C, Disanza A, Bravi L, Barrios Rodiles M, Corada M, Frittoli E, et al. The actin-binding protein EPS8 binds VE-cadherin and modulates YAP localization and signaling. J Cell Biol. 2015;211:1177-92 pubmed 出版商
  • 流式细胞仪; 人类; 图 8
  • 免疫细胞化学; 人类; 图 3
Oprea T, Sklar L, Agola J, Guo Y, Silberberg M, Roxby J, et al. Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases. PLoS ONE. 2015;10:e0142182 pubmed 出版商
  • 免疫印迹; 人类
Fujimura K, Choi S, Wyse M, Strnadel J, Wright T, Klemke R. Eukaryotic Translation Initiation Factor 5A (EIF5A) Regulates Pancreatic Cancer Metastasis by Modulating RhoA and Rho-associated Kinase (ROCK) Protein Expression Levels. J Biol Chem. 2015;290:29907-19 pubmed 出版商
  • 免疫印迹; 人类
Jamieson C, Lui C, Brocardo M, Martino Echarri E, Henderson B. Rac1 augments Wnt signaling by stimulating β-catenin-lymphoid enhancer factor-1 complex assembly independent of β-catenin nuclear import. J Cell Sci. 2015;128:3933-46 pubmed 出版商
  • 免疫印迹; 人类; 图 5
He S, Zhao Z, Yang Y, O Connell D, Zhang X, Oh S, et al. Truncating mutation in the autophagy gene UVRAG confers oncogenic properties and chemosensitivity in colorectal cancers. Nat Commun. 2015;6:7839 pubmed 出版商
  • 免疫印迹; 人类
Hahn C, Scott D, Xu X, Roda M, Payne G, Wells J, et al. The matrikine N-α-PGP couples extracellular matrix fragmentation to endothelial permeability. Sci Adv. 2015;1: pubmed
  • 免疫印迹; 人类; 图 7
Newell Litwa K, Badoual M, Asmussen H, Patel H, Whitmore L, Horwitz A. ROCK1 and 2 differentially regulate actomyosin organization to drive cell and synaptic polarity. J Cell Biol. 2015;210:225-42 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4
Whalley H, Porter A, Diamantopoulou Z, White G, Castañeda Saucedo E, Malliri A. Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation. Nat Commun. 2015;6:7437 pubmed 出版商
  • 免疫印迹; 人类
Yamana S, Tokiyama A, Mizutani K, Hirata K, Takai Y, Rikitake Y. The Cell Adhesion Molecule Necl-4/CADM4 Serves as a Novel Regulator for Contact Inhibition of Cell Movement and Proliferation. PLoS ONE. 2015;10:e0124259 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Yuan P, Zhang H, Cai C, Zhu S, Zhou Y, Yang X, et al. Chondroitin sulfate proteoglycan 4 functions as the cellular receptor for Clostridium difficile toxin B. Cell Res. 2015;25:157-68 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Delloye Bourgeois C, Jacquier A, Charoy C, Reynaud F, Nawabi H, Thoinet K, et al. PlexinA1 is a new Slit receptor and mediates axon guidance function of Slit C-terminal fragments. Nat Neurosci. 2015;18:36-45 pubmed 出版商
  • 免疫沉淀; 人类
van Adrichem A, Fagerholm A, Turunen L, Lehto A, Saarela J, Koskinen A, et al. Discovery of MINC1, a GTPase-activating protein small molecule inhibitor, targeting MgcRacGAP. Comb Chem High Throughput Screen. 2015;18:3-17 pubmed
  • 免疫印迹; 人类
Kovacs I, Horvath M, Kovacs T, Somogyi K, Tretter L, Geiszt M, et al. Comparison of proton channel, phagocyte oxidase, and respiratory burst levels between human eosinophil and neutrophil granulocytes. Free Radic Res. 2014;48:1190-9 pubmed 出版商
  • 免疫印迹; 人类; 图 s1
Takeda A, Oberoi Khanuja T, Glatz G, Schulenburg K, Scholz R, Carpy A, et al. Ubiquitin-dependent regulation of MEKK2/3-MEK5-ERK5 signaling module by XIAP and cIAP1. EMBO J. 2014;33:1784-801 pubmed 出版商
  • 免疫印迹; 人类
Zhong J, Bach C, Shum M, O Neill G. NEDD9 regulates 3D migratory activity independent of the Rac1 morphology switch in glioma and neuroblastoma. Mol Cancer Res. 2014;12:264-73 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 图 1
Delaney M, Liu J, Zheng Y, Berndt M, Du X. The role of Rac1 in glycoprotein Ib-IX-mediated signal transduction and integrin activation. Arterioscler Thromb Vasc Biol. 2012;32:2761-8 pubmed 出版商
Luo W, Song Z, Sun H, Liang J, Zhao S. Bergamottin, a natural furanocoumarin abundantly present in grapefruit juice, suppresses the invasiveness of human glioma cells via inactivation of Rac1 signaling. Oncol Lett. 2018;15:3259-3266 pubmed 出版商
Kroh H, Chandrasekaran R, Zhang Z, Rosenthal K, Woods R, Jin X, et al. A neutralizing antibody that blocks delivery of the enzymatic cargo of Clostridium difficile toxin TcdB into host cells. J Biol Chem. 2018;293:941-952 pubmed 出版商
Zhang Y, Li J, Li B, Wang J, Liu C. Mycobacterium tuberculosis Mce3C promotes mycobacteria entry into macrophages through activation of ?2 integrin-mediated signalling pathway. Cell Microbiol. 2017;: pubmed 出版商
Smith K, Rajgor D, Hanley J. Differential regulation of the Rac1 GTPase-activating protein (GAP) BCR during oxygen/glucose deprivation in hippocampal and cortical neurons. J Biol Chem. 2017;292:20173-20183 pubmed 出版商
He R, Peng J, Yuan P, Yang J, Wu X, Wang Y, et al. Glucosyltransferase Activity of Clostridium difficile Toxin B Triggers Autophagy-mediated Cell Growth Arrest. Sci Rep. 2017;7:10532 pubmed 出版商
Hernández Vásquez M, Adame García S, Hamoud N, Chidiac R, Reyes Cruz G, Gratton J, et al. Cell adhesion controlled by adhesion G protein-coupled receptor GPR124/ADGRA2 is mediated by a protein complex comprising intersectins and Elmo-Dock. J Biol Chem. 2017;292:12178-12191 pubmed 出版商
Schelle I, Bruening J, Buetepage M, Genth H. Role of p38alpha/beta MAP Kinase in Cell Susceptibility to Clostridium sordellii Lethal Toxin and Clostridium difficile Toxin B. Toxins (Basel). 2016;9: pubmed 出版商
Marei H, Carpy A, Macek B, Malliri A. Proteomic analysis of Rac1 signaling regulation by guanine nucleotide exchange factors. Cell Cycle. 2016;15:1961-74 pubmed 出版商
Rocca D, Hanley J. PICK1 links AMPA receptor stimulation to Cdc42. Neurosci Lett. 2015;585:155-9 pubmed 出版商
Cai K, Mulatz K, Ard R, Nguyen T, Gee S. Increased diacylglycerol kinase ? expression in human metastatic colon cancer cells augments Rho GTPase activity and contributes to enhanced invasion. BMC Cancer. 2014;14:208 pubmed 出版商
Chen P, Schauer K, Kong C, Harding A, Goud B, Stahl P. Rab5 isoforms orchestrate a "division of labor" in the endocytic network; Rab5C modulates Rac-mediated cell motility. PLoS ONE. 2014;9:e90384 pubmed 出版商
Ungefroren H, Sebens S, Giehl K, Helm O, Groth S, Fandrich F, et al. Rac1b negatively regulates TGF-?1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling. Oncotarget. 2014;5:277-90 pubmed
Berger A, Hoelbl Kovacic A, Bourgeais J, Hoefling L, Warsch W, Grundschober E, et al. PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis. Leukemia. 2014;28:629-41 pubmed 出版商
Yefimova M, Messaddeq N, Harnois T, Meunier A, Clarhaut J, Noblanc A, et al. A chimerical phagocytosis model reveals the recruitment by Sertoli cells of autophagy for the degradation of ingested illegitimate substrates. Autophagy. 2013;9:653-66 pubmed 出版商
Taniuchi K, Yokotani K, Saibara T. BART inhibits pancreatic cancer cell invasion by PKC? inactivation through binding to ANX7. PLoS ONE. 2012;7:e35674 pubmed 出版商
Greciano P, Moyano J, Buschmann M, Tang J, Lu Y, Rudnicki J, et al. Laminin 511 partners with laminin 332 to mediate directional migration of Madin-Darby canine kidney epithelial cells. Mol Biol Cell. 2012;23:121-36 pubmed 出版商
Vockel M, Pollok S, Breitenbach U, Ridderbusch I, Kreienkamp H, Brandner J. Somatostatin inhibits cell migration and reduces cell counts of human keratinocytes and delays epidermal wound healing in an ex vivo wound model. PLoS ONE. 2011;6:e19740 pubmed 出版商
Khusial P, Vadla B, Krishnan H, Ramlall T, Shen Y, Ichikawa H, et al. Src activates Abl to augment Robo1 expression in order to promote tumor cell migration. Oncotarget. 2010;1:198-209 pubmed
Papatheodorou P, Zamboglou C, Genisyuerek S, Guttenberg G, Aktories K. Clostridial glucosylating toxins enter cells via clathrin-mediated endocytosis. PLoS ONE. 2010;5:e10673 pubmed 出版商
产品信息
Cat.# :
610650
品牌 :
BD Transduction Laboratories
名称 :
Ras相关C3肉毒杆菌毒素底物1
格式 :
纯化
克隆 :
102/Ras相关C3肉毒杆菌毒素底物1
抗体亚型 :
Ms IgG 2b
反应 :
Hu , Ms , Rat , Dog , Chick
浓度 :
250微克/毫升
Apps :
IF, 免疫组化, 免疫印迹
规格 :
50微克
状态 :
RUO
更多信息或购买 :
公司信息
碧迪BD
上海市南京西路1168号中信泰富广场30楼
http://www.bd.com/china
021-32104610