产品简要
公司名称 :
Alomone Labs
产品类型 :
抗体
产品名称 :
豚鼠抗PSD-95抗体
目录 :
APZ-009-GP
规格 :
1 X 0.2毫升
价格 :
673美元
克隆性 :
多克隆
宿主 :
豚鼠
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹
更多信息或购买 :
图像
图像 1 :
![Alomone Labs APZ-009-GP 图像 1](http://www.labome.com/product/Alomone-Labs/6380844_0.jpg)
Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4) brain membranes: - 1-2. Guinea Pig Anti-PSD-95 Antibody (#APZ-009-GP), (1:200).3-4. Guinea Pig Anti-PSD-95 Antibody, preincubated with PSD-95 Blocking Peptide (BLP-PZ009).
产品信息
SKU号 :
APZ-009-GP_1_0.2_ml
ParentSKU :
APZ-009-GP
Taxonomy Node :
Primary Antibody>Intracellular>Non-Labeled
Action :
Insert
产品名称 :
豚鼠抗PSD-95抗体
产品描述 :
Guinea Pig Anti-PSD-95 Antibody (#APZ-009-GP) is a highly specific antibody directed against an epitope of the human protein. The antibody can be used in western blot applications. It has been designed to recognize PSD-95 from rat, mouse, and human samples.
n
nThe antigen used to immunize guinea pigs is the same as Anti-PSD-95 Antibody (#APZ-009) raised in rabbit. Our line of guinea pig antibodies enables more flexibility with our products such as multiplex staining studies, immunoprecipitation and more.
Short Description :
A豚鼠多克隆抗体PSD-95
Negative Control :
BLP-PZ009
同义词 :
Postsynaptic density protein 95, Discs large homolog 4, DLG4, Synapse-associated protein 90, SAP-90, Tax interaction protein 15, MRD62
靶标名 :
PSD-95
标记/共轭标签 :
未共轭
应用 :
免疫印迹
宿主 :
豚鼠
克隆性 :
多克隆
抗体亚型 :
豚鼠总数IgG
基因符号 :
DLG4
反应物种 :
人类(试验);小鼠(试验);大鼠(试验)
同源 :
Rat, mouse – identical.
靶标/背景信息 :
β-Adrenergic receptors (βAR) belong to the superfamily of G-protein coupled receptors (GPCRs). βAR stimulation by the sympathetic nervous system or circulating catecholamines is involved in peripheral blood circulation, metabolic regulation, muscle contraction, and central neural activities. In the heart, acute βAR stimulation serves as the most powerful means to regulate cardiac output in response to a fight-or-flight situation.
There are three βAR subtypes, β1AR, β2AR and β3AR, in cardiac myocytes1. The receptors consist of seven membrane-spanning domains, three intra- and three extracellular loops, an extracellular N-terminal domain, and an intracellular C-terminal tail2.
β1AR is the predominant receptor subtype expressed in human cardiomyocytes. β1AR is also expressed in the kidney3. It has been implicated in adipogenesis and memory formation4.
β1AR has been widely connected with heart disease. Both the downregulation and overstimulation of β1AR have been connected to myocyte apoptosis. In addition, chronic heart failure is characterized by abnormalities in β1AR signal transduction. It was demonstrated that heart failure is also inducible in animal models by overexpression of components of the β1AR signal transduction cascade. Transgenic mice overexpressing β1AR develop, with aging, heart failure similar to that observed in dilated cardiomyopathy in humans5.
免疫原 :
合成肽
区域 :
intracellular
Loop :
Intracellular
序列 :
(C)KDWGSSSGSQGRED, corresponding to amino acid residues 505-518 of human PSD-95
序列文本 :
Peptide (C)KDWGSSSGSQGRED, corresponding to amino acid residues 505-518 of human PSD-95 (Accession P78352). Intracellular, between the SH3 and the GK-like domains.
Primary Size (Size+Units) :
1 X 0.2毫升
浓度 :
0.8毫克/毫升
浓度 :
08毫克/毫升
缓冲液 :
磷酸盐缓冲液(PBS)
pH值 :
pH值7.4
防腐剂 :
1% BSA, 0.05% NaN3 (% of reconstituted antibody)
Additive(s) :
Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
格式(液体/冻干) :
冻干粉末
纯化来源(杂交瘤细胞, 腹水 :
Affinity purified on immobilized antigen
储存温度 :
-20°C
UniProt数据库 :
P78352
储存和重组 :
Reconstitution: 1 X 0.2 ml double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C, as long as it is in its original form, it can last a minimum of 3 years this way. The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
包装规格 :
1
产品规格/规格 :
0.2
单位 :
毫升
标价美国[美元] :
673美元
更多信息或购买 :
公司信息
![logo](http://aws.labome.com/img/78.gif)
Alomone Labs
Jerusalem BioPark (JBP), Hadassah Ein Kerem
P.O. Box 4287
Jerusalem 9104201
P.O. Box 4287
Jerusalem 9104201
info@alomone.com
http://www.alomone.com972-2-587-2202
公司总部: 以色列
Alomone Labs公司成立于1989年,在离子通道、GPCR及神经信号通路研究等领域占据全球领先地位。