Geneka Biotechnology

抗体

RAR-M抗体(单克隆抗体)

39971

100微克

350美元

单克隆

小鼠

未共轭

9M-NM-1-9A6

人类, 小鼠

免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, EMSA

RAR-M抗体(单克隆抗体)

小鼠

单克隆

100微克

350美元

9M-NM-1-9A6

IgG1k

人类, 小鼠

Retinoic acid receptors (RAR) are nuclear receptors that are activated by both all-trans retinoic acid and 9-cis retinoic acid. There are three retinoic acid receptors (RAR), RAR-M-NM-1, RAR-M-NM-2 and RAR-M-NM-3. RAR-M-NM-1 (Nuclear receptor subfamily 1 group B member 1, NR1B1) interacts with NCoA3, NCoA6, NCoA7 and MLL to activate transcription of target genes. Chromosomal aberrations of RAR-M-NM-1 are sometimes involved in Promyelocytic leukemia.

This RAR-a antibody was raised against a recombinant protein corresponding to amino acids 420-443 (the F region) of human RARa.

酶联免疫吸附测定, EMSA, 免疫细胞化学, 免疫组化, 免疫沉淀, 免疫印迹

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

References: This antibody has been used in the following references: EMSA: Bollig F et al. (2009) Development 136: 2883-2892.IHC: Reichrath J et al. (1997) Histochem J 29: 127-133.WB: Quere R et al. (2007) Blood 109: 4450-4460.