产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗PGC1甲抗体
目录 :
ab54481
规格 :
50微升
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
文章摘录数: 70
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 8a
  • 免疫印迹; 小鼠; 1:1000; 图 8b
Yeh C, Liu H, Lee M, Leu Y, Chiang W, Chang H, et al. Phytochemical‑rich herbal formula ATG‑125 protects against sucrose‑induced gastrocnemius muscle atrophy by rescuing Akt signaling and improving mitochondrial dysfunction in young adult mice. Mol Med Rep. 2022;25: pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000
Hu D, Sun X, Magpusao A, Fedorov Y, Thompson M, Wang B, et al. Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease. Nat Commun. 2021;12:5305 pubmed 出版商
  • 免疫沉淀; 小鼠; 图 3d
  • 免疫印迹; 小鼠; 1:500-1:2000; 图 3b
Chiang S, Braidy N, Maleki S, Lal S, Richardson D, Huang M. Mechanisms of impaired mitochondrial homeostasis and NAD+ metabolism in a model of mitochondrial heart disease exhibiting redox active iron accumulation. Redox Biol. 2021;46:102038 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Vieira Lara M, Dommerholt M, Zhang W, Blankestijn M, Wolters J, Abegaz F, et al. Age-related susceptibility to insulin resistance arises from a combination of CPT1B decline and lipid overload. BMC Biol. 2021;19:154 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s3b
Liu H, Zang P, Lee I, Anderson B, Christiani A, Strait Bodey L, et al. Growth hormone secretagogue receptor-1a mediates ghrelin's effects on attenuating tumour-induced loss of muscle strength but not muscle mass. J Cachexia Sarcopenia Muscle. 2021;12:1280-1295 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2b, 2g
Mu W, Qian S, Song Y, Yang L, Song S, Yang Q, et al. BMP4-mediated browning of perivascular adipose tissue governs an anti-inflammatory program and prevents atherosclerosis. Redox Biol. 2021;43:101979 pubmed 出版商
  • 免疫印迹; 小鼠; 1:100; 图 4g
Rupert J, Narasimhan A, Jengelley D, Jiang Y, Liu J, Au E, et al. Tumor-derived IL-6 and trans-signaling among tumor, fat, and muscle mediate pancreatic cancer cachexia. J Exp Med. 2021;218: pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 s1f
Hsiao Y, Shimizu I, Wakasugi T, Yoshida Y, Ikegami R, Hayashi Y, et al. Cardiac mitofusin-1 is reduced in non-responding patients with idiopathic dilated cardiomyopathy. Sci Rep. 2021;11:6722 pubmed 出版商
  • 免疫印迹; 小鼠; 1:50; 图 3d
Miao Y, Qin H, Zhong Y, Huang K, Rao C. Novel adipokine asprosin modulates browning and adipogenesis in white adipose tissue. J Endocrinol. 2021;249:83-93 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3c
Wallace M, Aguirre N, Marcotte G, Marshall A, Baehr L, Hughes D, et al. The ketogenic diet preserves skeletal muscle with aging in mice. Aging Cell. 2021;20:e13322 pubmed 出版商
  • 免疫印迹; 人类; 图 2k
Galbraith L, Mui E, Nixon C, Hedley A, Strachan D, Mackay G, et al. PPAR-gamma induced AKT3 expression increases levels of mitochondrial biogenesis driving prostate cancer. Oncogene. 2021;40:2355-2366 pubmed 出版商
  • 免疫细胞化学; 人类; 1:300
Mehta A, Gregory J, Dando O, Carter R, Burr K, Nanda J, et al. Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis. Acta Neuropathol. 2021;141:257-279 pubmed 出版商
  • 免疫印迹; 大鼠; 图 3d
Shah D, Nisr R, Stretton C, Krasteva Christ G, Hundal H. Caveolin-3 deficiency associated with the dystrophy P104L mutation impairs skeletal muscle mitochondrial form and function. J Cachexia Sarcopenia Muscle. 2020;11:838-858 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4d
Ghosh A, Bhattacharjee S, Chowdhuri S, Mallick A, Rehman I, Basu S, et al. SCAN1-TDP1 trapping on mitochondrial DNA promotes mitochondrial dysfunction and mitophagy. Sci Adv. 2019;5:eaax9778 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3b
Zuo Z, Liu Z, Gao T, Yin Y, Wang Z, Hou Y, et al. Prolonged inorganic arsenic exposure via drinking water impairs brown adipose tissue function in mice. Sci Total Environ. 2019;668:310-317 pubmed 出版商
  • 免疫印迹; 人类; 图 4d
Zhang C, Deng J, Liu D, Tuo X, Xiao L, Lai B, et al. Nuciferine ameliorates hepatic steatosis in high-fat diet/streptozocin-induced diabetic mice through a PPARα/PPARγ coactivator-1α pathway. Br J Pharmacol. 2018;175:4218-4228 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3b
Vargas D, Lopez C, Acero E, Benítez E, Wintaco A, Camacho J, et al. Thermogenic capacity of human periaortic adipose tissue is transformed by body weight. PLoS ONE. 2018;13:e0194269 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Sato M, Kawana K, Adachi K, Fujimoto A, Yoshida M, Nakamura H, et al. Detachment from the primary site and suspension in ascites as the initial step in metabolic reprogramming and metastasis to the omentum in ovarian cancer. Oncol Lett. 2018;15:1357-1361 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1f
Velázquez Villegas L, Perino A, Lemos V, Zietak M, Nomura M, Pols T, et al. TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue. Nat Commun. 2018;9:245 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3b
Lizcano F, Vargas D, Gomez A, Torrado A. Human ADMC-Derived Adipocyte Thermogenic Capacity Is Regulated by IL-4 Receptor. Stem Cells Int. 2017;2017:2767916 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2d
Le N, Kim C, Tu T, Kim B, Park T, Park J, et al. Absence of 4-1BB reduces obesity-induced atrophic response in skeletal muscle. J Inflamm (Lond). 2017;14:9 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 6B
Kodo K, Sugimoto S, Nakajima H, Mori J, Itoh I, Fukuhara S, et al. Erythropoietin (EPO) ameliorates obesity and glucose homeostasis by promoting thermogenesis and endocrine function of classical brown adipose tissue (BAT) in diet-induced obese mice. PLoS ONE. 2017;12:e0173661 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5a
Kong Q, Zhang H, Zhao T, Zhang W, Yan M, Dong X, et al. Tangshen formula attenuates hepatic steatosis by inhibiting hepatic lipogenesis and augmenting fatty acid oxidation in db/db mice. Int J Mol Med. 2016;38:1715-1726 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 6d
Doan K, Kinyua A, Yang D, Ko C, Moh S, Shong K, et al. FoxO1 in dopaminergic neurons regulates energy homeostasis and targets tyrosine hydroxylase. Nat Commun. 2016;7:12733 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5f
Zhang C, Weng Y, Shi F, Jin W. The Engrailed-1 Gene Stimulates Brown Adipogenesis. Stem Cells Int. 2016;2016:7369491 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 S7
Basisty N, Dai D, Gagnidze A, Gitari L, Fredrickson J, Maina Y, et al. Mitochondrial-targeted catalase is good for the old mouse proteome, but not for the young: 'reverse' antagonistic pleiotropy?. Aging Cell. 2016;15:634-45 pubmed 出版商
  • 免疫印迹; 大鼠; 图 4
Huang Y, Chen C, Tang K, Sheen J, Tiao M, Tain Y, et al. Postnatal High-Fat Diet Increases Liver Steatosis and Apoptosis Threatened by Prenatal Dexamethasone through the Oxidative Effect. Int J Mol Sci. 2016;17:369 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6
Liu Z, Gan L, Chen Y, Luo D, Zhang Z, Cao W, et al. Mark4 promotes oxidative stress and inflammation via binding to PPARγ and activating NF-κB pathway in mice adipocytes. Sci Rep. 2016;6:21382 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Audet Walsh Ã, Papadopoli D, Gravel S, Yee T, Bridon G, Caron M, et al. The PGC-1α/ERRα Axis Represses One-Carbon Metabolism and Promotes Sensitivity to Anti-folate Therapy in Breast Cancer. Cell Rep. 2016;14:920-931 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1500; 图 4b
Zhang H, Wang X, Wu Z, Liu H, Chen W, Zhang Z, et al. Beneficial effect of farnesoid X receptor activation on metabolism in a diabetic rat model. Mol Med Rep. 2016;13:2135-42 pubmed 出版商
Chatterjee A, Sakallioglu I, Murthy D, Kosmacek E, Singh P, McDonald J, et al. MnTE-2-PyP protects fibroblast mitochondria from hyperglycemia and radiation exposure. Redox Biol. 2022;52:102301 pubmed 出版商
Yin Z, Sun J, Cui H, Jiang C, Zhang Y, Lee S, et al. Tannin Supplementation Improves Oocyte Cytoplasmic Maturation and Subsequent Embryo Development in Pigs. Antioxidants (Basel). 2021;10: pubmed 出版商
Hsieh P, Yu C, Chu P, Hsieh P. Verbascoside Protects Gingival Cells against High Glucose-Induced Oxidative Stress via PKC/HMGB1/RAGE/NFκB Pathway. Antioxidants (Basel). 2021;10: pubmed 出版商
Martinez Bernabe T, Sastre Serra J, Ciobu N, Oliver J, Pons D, Roca P. Estrogen Receptor Beta (ERβ) Maintains Mitochondrial Network Regulating Invasiveness in an Obesity-Related Inflammation Condition in Breast Cancer. Antioxidants (Basel). 2021;10: pubmed 出版商
Khin P, Hong Y, Yeon M, Lee D, Lee J, Jun H. Dulaglutide improves muscle function by attenuating inflammation through OPA-1-TLR-9 signaling in aged mice. Aging (Albany NY). 2021;13:21962-21974 pubmed 出版商
Jo D, Yoon G, Song J. Role of Exendin-4 in Brain Insulin Resistance, Mitochondrial Function, and Neurite Outgrowth in Neurons under Palmitic Acid-Induced Oxidative Stress. Antioxidants (Basel). 2021;10: pubmed 出版商
Kato M, Abdollahi M, Tunduguru R, Tsark W, Chen Z, Wu X, et al. miR-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via FIS1. Commun Biol. 2021;4:30 pubmed 出版商
Li Y, Zou S, Ding H, Hao N, Huang Y, Tang J, et al. Low Expression of Sirtuin 1 in the Dairy Cows with Mild Fatty Liver Alters Hepatic Lipid Metabolism. Animals (Basel). 2020;10: pubmed 出版商
Li J, Yu D, Chen S, Liu Y, Shi J, Zhang J, et al. Sirt6 opposes glycochenodeoxycholate-induced apoptosis of biliary epithelial cells through the AMPK/PGC-1α pathway. Cell Biosci. 2020;10:43 pubmed 出版商
Liu D, Ma Z, Xu L, Zhang X, Qiao S, Yuan J. PGC1α activation by pterostilbene ameliorates acute doxorubicin cardiotoxicity by reducing oxidative stress via enhancing AMPK and SIRT1 cascades. Aging (Albany NY). 2019;11:10061-10073 pubmed 出版商
Zhao L, Chen X, Feng Y, Wang G, Nawaz I, Hu L, et al. COX7A1 suppresses the viability of human non-small cell lung cancer cells via regulating autophagy. Cancer Med. 2019;8:7762-7773 pubmed 出版商
Miao J, Liu J, Niu J, Zhang Y, Shen W, Luo C, et al. Wnt/β-catenin/RAS signaling mediates age-related renal fibrosis and is associated with mitochondrial dysfunction. Aging Cell. 2019;18:e13004 pubmed 出版商
Lee G, Uddin M, Kim Y, Ko M, Yu I, Ha H. PGC-1α, a potential therapeutic target against kidney aging. Aging Cell. 2019;18:e12994 pubmed 出版商
Reyes Fermín L, Avila Rojas S, Aparicio Trejo O, Tapia E, Rivero I, Pedraza Chaverri J. The Protective Effect of Alpha-Mangostin against Cisplatin-Induced Cell Death in LLC-PK1 Cells is Associated to Mitochondrial Function Preservation. Antioxidants (Basel). 2019;8: pubmed 出版商
Zhuang C, Zhuang C, Luo X, Huang X, Yao L, Li J, et al. N6-methyladenosine demethylase FTO suppresses clear cell renal cell carcinoma through a novel FTO-PGC-1α signalling axis. J Cell Mol Med. 2019;23:2163-2173 pubmed 出版商
Ivarsson N, Mattsson C, Cheng A, Bruton J, Ekblom B, Lanner J, et al. SR Ca2+ leak in skeletal muscle fibers acts as an intracellular signal to increase fatigue resistance. J Gen Physiol. 2019;151:567-577 pubmed 出版商
McMurphy T, Huang W, Liu X, Siu J, Queen N, Xiao R, et al. Hypothalamic gene transfer of BDNF promotes healthy aging in mice. Aging Cell. 2019;18:e12846 pubmed 出版商
Choi J, Song N, Lee A, Lee D, Seo M, Kim S, et al. Oxyresveratrol Increases Energy Expenditure through Foxo3a-Mediated Ucp1 Induction in High-Fat-Diet-Induced Obese Mice. Int J Mol Sci. 2018;20: pubmed 出版商
Wahl D, Solon Biet S, Wang Q, Wali J, Pulpitel T, Clark X, et al. Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice. Cell Rep. 2018;25:2234-2243.e6 pubmed 出版商
Wang S, Zhao Z, Feng X, Cheng Z, Xiong Z, Wang T, et al. Melatonin activates Parkin translocation and rescues the impaired mitophagy activity of diabetic cardiomyopathy through Mst1 inhibition. J Cell Mol Med. 2018;22:5132-5144 pubmed 出版商
McMurphy T, Huang W, Queen N, Ali S, Widstrom K, Liu X, et al. Implementation of environmental enrichment after middle age promotes healthy aging. Aging (Albany NY). 2018;10:1698-1721 pubmed 出版商
Yu B, Huo L, Liu Y, Deng P, Szymanski J, Li J, et al. PGC-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ. Cell Stem Cell. 2018;23:193-209.e5 pubmed 出版商
Bae J. Aerobic Exercise Increases Meteorin-Like Protein in Muscle and Adipose Tissue of Chronic High-Fat Diet-Induced Obese Mice. Biomed Res Int. 2018;2018:6283932 pubmed 出版商
Yamashita Y, Nakada S, Yoshihara T, Nara T, Furuya N, Miida T, et al. Perlecan, a heparan sulfate proteoglycan, regulates systemic metabolism with dynamic changes in adipose tissue and skeletal muscle. Sci Rep. 2018;8:7766 pubmed 出版商
He F, Jin J, Qin Q, Zheng Y, Li T, Zhang Y, et al. Resistin Regulates Fatty Acid Β Oxidation by Suppressing Expression of Peroxisome Proliferator Activator Receptor Gamma-Coactivator 1α (PGC-1α). Cell Physiol Biochem. 2018;46:2165-2172 pubmed 出版商
Kuang Y, Han X, Xu M, Yang Q. Oxaloacetate induces apoptosis in HepG2 cells via inhibition of glycolysis. Cancer Med. 2018;7:1416-1429 pubmed 出版商
Drury E, Zsengellér Z, Stillman I, Khankin E, Pavlakis M, Parikh S. Renal PGC1α May Be Associated with Recovery after Delayed Graft Function. Nephron. 2018;138:303-309 pubmed 出版商
Ishimoto Y, Inagi R, Yoshihara D, Kugita M, Nagao S, Shimizu A, et al. Mitochondrial Abnormality Facilitates Cyst Formation in Autosomal Dominant Polycystic Kidney Disease. Mol Cell Biol. 2017;37: pubmed 出版商
Kim S, Yang C, Lee H, Kim J, Kim Y, Kim Y, et al. ESRRA (estrogen-related receptor α) is a key coordinator of transcriptional and post-translational activation of autophagy to promote innate host defense. Autophagy. 2018;14:152-168 pubmed 出版商
Guo X, Li F, Xu Z, Yin A, Yin H, Li C, et al. DOCK2 deficiency mitigates HFD-induced obesity by reducing adipose tissue inflammation and increasing energy expenditure. J Lipid Res. 2017;58:1777-1784 pubmed 出版商
De Jong A, Carreira S, Na N, Carillion A, Jiang C, Beuvin M, et al. Diaphragmatic function is enhanced in fatty and diabetic fatty rats. PLoS ONE. 2017;12:e0174043 pubmed 出版商
Martin J, Kephart W, Haun C, McCloskey A, Shake J, Mobley C, et al. Impact of external pneumatic compression target inflation pressure on transcriptome-wide RNA expression in skeletal muscle. Physiol Rep. 2016;4: pubmed
Dölle C, Flønes I, Nido G, Miletic H, Osuagwu N, Kristoffersen S, et al. Defective mitochondrial DNA homeostasis in the substantia nigra in Parkinson disease. Nat Commun. 2016;7:13548 pubmed 出版商
Shintaku J, Peterson J, Talbert E, Gu J, Ladner K, Williams D, et al. MyoD Regulates Skeletal Muscle Oxidative Metabolism Cooperatively with Alternative NF-?B. Cell Rep. 2016;17:514-526 pubmed 出版商
Chen M, Wang M, Yang Q, Wang M, Wang Z, Zhu Y, et al. Antioxidant effects of hydroxysafflor yellow A and acetyl-11-keto-?-boswellic acid in combination on isoproterenol-induced myocardial injury in rats. Int J Mol Med. 2016;37:1501-10 pubmed 出版商
Guan Y, Cui Z, Sun B, Han L, Li C, Chen L. Celastrol attenuates oxidative stress in the skeletal muscle of diabetic rats by regulating the AMPK-PGC1?-SIRT3 signaling pathway. Int J Mol Med. 2016;37:1229-38 pubmed 出版商
Tran M, Zsengellér Z, Berg A, Khankin E, Bhasin M, Kim W, et al. PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection. Nature. 2016;531:528-32 pubmed 出版商
Camarda R, Zhou A, Kohnz R, Balakrishnan S, Mahieu C, Anderton B, et al. Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer. Nat Med. 2016;22:427-32 pubmed 出版商
Zhou Y, Gu P, Shi W, Li J, Hao Q, Cao X, et al. MicroRNA-29a induces insulin resistance by targeting PPARδ in skeletal muscle cells. Int J Mol Med. 2016;37:931-8 pubmed 出版商
Vargas D, Shimokawa N, Kaneko R, Rosales W, Parra A, Castellanos Ã, et al. Regulation of human subcutaneous adipocyte differentiation by EID1. J Mol Endocrinol. 2016;56:113-22 pubmed 出版商
产品信息
目录号 :
ab54481
ItemName :
抗PGC1甲抗体
类别 :
抗体
宿主 :
克隆性 :
多克隆
共轭标签 :
未共轭
规格 :
50微升
物种摘要 :
Hu, Ms, Rat, Zfsh
应用摘要 :
酶联免疫吸附测定, 免疫细胞化学/IF, 免疫组化-P, 免疫印迹
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。