| 出版应用/物种/样本/稀释 | 参考文献 |
|---|
| Lü Z, Liu H, Song N, Liang Y, Zhu J, Chen J, et al. METTL14 aggravates podocyte injury and glomerulopathy progression through N6-methyladenosine-dependent downregulating of Sirt1. Cell Death Dis. 2021;12:881 pubmed 出版商 |
| Yue M, Liu T, Yan G, Luo X, Wang L. LINC01605, regulated by the EP300-SMYD2 complex, potentiates the binding between METTL3 and SPTBN2 in colorectal cancer. Cancer Cell Int. 2021;21:504 pubmed 出版商 |
- 免疫组化; 人类; 图 2d
- 免疫印迹; 人类; 图 3a
| Wen J, Zhang G, Meng Y, Zhang L, Jiang M, Yu Z. RNA m6A methyltransferase METTL3 promotes colorectal cancer cell proliferation and invasion by regulating Snail expression. Oncol Lett. 2021;22:711 pubmed 出版商 |
| Zhao C, Ling X, Xia Y, Yan B, Guan Q. The m6A methyltransferase METTL3 controls epithelial-mesenchymal transition, migration and invasion of breast cancer through the MALAT1/miR-26b/HMGA2 axis. Cancer Cell Int. 2021;21:441 pubmed 出版商 |
- 核糖核酸免疫沉淀; 人类; 图 3i
- 免疫印迹; 人类; 图 s4f
| Liu Z, Wang T, She Y, Wu K, Gu S, Li L, et al. N6-methyladenosine-modified circIGF2BP3 inhibits CD8+ T-cell responses to facilitate tumor immune evasion by promoting the deubiquitination of PD-L1 in non-small cell lung cancer. Mol Cancer. 2021;20:105 pubmed 出版商 |
| Pan Z, Wang B, Hou D, You R, Wang X, Xie W, et al. METTL3 mediates bone marrow mesenchymal stem cell adipogenesis to promote chemoresistance in acute myeloid leukaemia. FEBS Open Bio. 2021;11:1659-1672 pubmed 出版商 |
| Hua Y, Zhang K, Sheng J, Ning Z, Li Y, Shi W, et al. NUCB1 Suppresses Growth and Shows Additive Effects With Gemcitabine in Pancreatic Ductal Adenocarcinoma via the Unfolded Protein Response. Front Cell Dev Biol. 2021;9:641836 pubmed 出版商 |
| Ma L, Chen T, Zhang X, Miao Y, Tian X, Yu K, et al. The m6A reader YTHDC2 inhibits lung adenocarcinoma tumorigenesis by suppressing SLC7A11-dependent antioxidant function. Redox Biol. 2021;38:101801 pubmed 出版商 |
| Yang Z, Jiang X, Li D, Jiang X. HBXIP promotes gastric cancer via METTL3-mediated MYC mRNA m6A modification. Aging (Albany NY). 2020;12:24967-24982 pubmed 出版商 |
- 免疫组化; 小鼠; 1:100-1:500; 图 2b
| Xi L, Carroll T, Matos I, Luo J, Polak L, Pasolli H, et al. m6A RNA methylation impacts fate choices during skin morphogenesis. elife. 2020;9: pubmed 出版商 |
| Liu J, Dou X, Chen C, Chen C, Liu C, Xu M, et al. N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription. Science. 2020;367:580-586 pubmed 出版商 |
| Chen R, Chen X, Xia L, Zhang J, Pan Z, Ma X, et al. N6-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis. Nat Commun. 2019;10:4695 pubmed 出版商 |
| Song T, Yang Y, Wei H, Xie X, Lu J, Zeng Q, et al. Zfp217 mediates m6A mRNA methylation to orchestrate transcriptional and post-transcriptional regulation to promote adipogenic differentiation. Nucleic Acids Res. 2019;: pubmed 出版商 |
| Zhang J, Bai R, Li M, Ye H, Wu C, Wang C, et al. Excessive miR-25-3p maturation via N6-methyladenosine stimulated by cigarette smoke promotes pancreatic cancer progression. Nat Commun. 2019;10:1858 pubmed 出版商 |
| Du M, Zhang Y, Mao Y, Mou J, Zhao J, Xue Q, et al. MiR-33a suppresses proliferation of NSCLC cells via targeting METTL3 mRNA. Biochem Biophys Res Commun. 2017;482:582-589 pubmed 出版商 |
| Zhang D, Ning J, Okon I, Zheng X, Satyanarayana G, Song P, et al. Suppression of m6A mRNA modification by DNA hypermethylated ALKBH5 aggravates the oncological behavior of KRAS mutation/LKB1 loss lung cancer. Cell Death Dis. 2021;12:518 pubmed 出版商 |
| Zhang F, Yan Y, Cao X, Zhang J, Li Y, Guo C. Methylation of microRNA-338-5p by EED promotes METTL3-mediated translation of oncogene CDCP1 in gastric cancer. Aging (Albany NY). 2021;13:12224-12238 pubmed 出版商 |
| Fish L, Navickas A, Culbertson B, Xu Y, Nguyen H, Zhang S, et al. Nuclear TARBP2 Drives Oncogenic Dysregulation of RNA Splicing and Decay. Mol Cell. 2019;75:967-981.e9 pubmed 出版商 |
| Shi H, Zhang X, Weng Y, Lu Z, Liu Y, Lu Z, et al. m6A facilitates hippocampus-dependent learning and memory through YTHDF1. Nature. 2018;563:249-253 pubmed 出版商 |
| Zhang Z, Wang M, Xie D, Huang Z, Zhang L, Yang Y, et al. METTL3-mediated N6-methyladenosine mRNA modification enhances long-term memory consolidation. Cell Res. 2018;28:1050-1061 pubmed 出版商 |
| Choe J, Lin S, Zhang W, Liu Q, Wang L, Ramírez Moya J, et al. mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis. Nature. 2018;561:556-560 pubmed 出版商 |
| Wang C, Cui G, Liu X, Xu K, Wang M, Zhang X, et al. METTL3-mediated m6A modification is required for cerebellar development. PLoS Biol. 2018;16:e2004880 pubmed 出版商 |
