抗体

Aspartate Beta Hydroxylase (ASPH) Antibody

abx027012

80微升

多克隆

domestic rabbit

未共轭

免疫印迹, 酶联免疫吸附测定, 免疫组化

Aspartate Beta Hydroxylase (ASPH)

Aspartate Beta Hydroxylase (ASPH) Antibody

ASPH

Aspartate Beta Hydroxylase

一抗

兔

多克隆

未共轭

IgG

80微升

400微升

This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF) like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis.

Q12797

ASPH_HUMAN

hsa:444

9606.ENSP00000368767

Purified through a protein A column, followed by peptide affinity purification.

PBS含0.09% 叠氮化钠

酶联免疫吸附测定, 免疫印迹, 免疫组化

分成小份儿保存在-20°C。 避免反复冻融

液体

12352203

Shipped within 5-10 working days.

No